Butylboronic acid

CAS 4426-47-5CH3(CH2)3B(OH)2Chemical Synthesis

Butylboronic acid (CAS 4426-47-5), with the linear formula CH3(CH2)3B(OH)2 and a molecular weight of 101.94 g/mol, is a key organoborane reagent. This white crystalline solid finds significant utility in organic synthesis. It serves as a precursor for unsymmetric borinic acids and is instrumental in the preparation of chiral oxazaborolidines, which are valuable in asymmetric synthesis.

IUPAC: 1-Butaneboronic acid
Synonyms: 1-Butaneboronic acid

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Butylboronic acid (CH3(CH2)3B(OH)2) — chemical structure, CAS 4426-47-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Alkyl Boronic AcidsBoronic AcidsChemical SynthesisOrganometallic Reagents

01 /Applications

Precursor to Unsymmetrical Borinic Acids

Butylboronic acid is employed as a starting material in the synthesis of unsymmetrical borinic acids. These compounds can act as potent inhibitors for various enzymes, including serine proteases, making them of interest in biochemical research and drug discovery.

Synthesis of Chiral Oxazaborolidines

This reagent is utilised in the preparation of chiral oxazaborolidines. These cyclic boron compounds are well-established as efficient catalysts in asymmetric synthesis, particularly for enantioselective reductions.

Organometallic Reagent in Synthesis

As an alkyl boronic acid, Butylboronic acid functions as an organometallic reagent. It can participate in various coupling reactions and serves as a building block for introducing the n-butyl group into organic molecules.

02 /Properties

Molecular weight	101.94
Linear formula	CH3(CH2)3B(OH)2
Assay	97%
Application	A precursor to unsymmetric borinic acids, inhibitors of serine proteases.1 Reagent used to prepare chiral oxazaborolidines.2,3
Melting point	90-92 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

4426-47-5

MDL number

MFCD00002106

PubChem substance

24850030

Beilstein registry

1733489

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Butylboronic acid used for?

Butylboronic acid is used as a precursor to unsymmetric borinic acids, which can be inhibitors of serine proteases, and as a reagent to prepare chiral oxazaborolidines used in chemical synthesis.

What are the CAS number and formula for Butylboronic acid?

The CAS number for Butylboronic acid is 4426-47-5, and its linear formula is CH3(CH2)3B(OH)2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Butylboronic acid with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

How should Butylboronic acid be handled safely?

Handle Butylboronic acid with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a P1 (EN143) or N95 (US) type respirator filter if needed. It is classified with WGK 2 in Germany.

Is Butylboronic acid a controlled substance?

Based on the provided data, there is no indication that Butylboronic acid is a controlled substance.

How is Butylboronic acid packed and shipped?

Butylboronic acid is carefully packed to maintain its integrity during transit and is exported globally by Tech Serve Solutions in compliance with relevant regulations.

How can I request a quote or sample of Butylboronic acid?

To request a quote or sample of Butylboronic acid, please contact our sales team through the website or via direct inquiry, referencing CAS 4426-47-5.