3,3′-Dithiodipropionic acid
3,3′-Dithiodipropionic acid (CAS 1119-62-6), with the linear formula HOCOCH2CH2SSCH2CH2COOH and a molecular weight of 210.27 g/mol, is a difunctional carboxylic acid featuring a disulfide bond. This compound serves as a versatile building block in organic synthesis. It is particularly noted for its application as a capping agent in modifying the surfaces of nanoparticles, influencing their properties and interactions in various scientific contexts.
- IUPAC
- 2-Carboxyethyl disulfide,Bis(2-carboxyethyl) disulfide
- Synonyms
- 2-Carboxyethyl disulfideBis(2-carboxyethyl) disulfide

Nanoparticle Surface Modification
3,3′-Dithiodipropionic acid is employed as a capping agent to functionalise gold nanoparticle surfaces. This modification introduces charge and specific chemical properties, enabling tailored interactions and applications in areas such as sensing and catalysis.
Organic Synthesis Intermediate
As a difunctional carboxylic acid with a central disulfide linkage, it acts as a valuable intermediate in the synthesis of more complex organic molecules. Its structure allows for diverse chemical transformations and incorporation into various molecular architectures.
Material Science Research
The compound's ability to modify surfaces makes it relevant in material science research for developing new materials with specific surface characteristics. It can be used to control the self-assembly of molecules and the properties of interfaces.
| Molecular weight | 210.27 |
|---|---|
| Linear formula | HOCOCH2CH2SSCH2CH2COOH |
| Assay | 99% |
| Application | 3,3′-Dithiodipropionic acid was used as capping agent for introducing charge on gold nanoparticles surfaces1. |
| Melting point | 155-158 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3′-Dithiodipropionic acid primarily used for?
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3,3′-Dithiodipropionic acid is primarily used as a capping agent for modifying nanoparticle surfaces, such as gold nanoparticles, and as an intermediate in organic synthesis.
What is the CAS number and formula for 3,3′-Dithiodipropionic acid?
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The CAS number is 1119-62-6 and the linear formula is HOCOCH2CH2SSCH2CH2COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3′-Dithiodipropionic acid with an assay of 99%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 3,3′-Dithiodipropionic acid be handled safely?
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3,3′-Dithiodipropionic acid is classified as a skin irritant, eye irritant, and respiratory irritant. Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust. For eye contact, rinse cautiously with water for several minutes. If skin irritation occurs, seek medical advice.
Is 3,3′-Dithiodipropionic acid a controlled substance?
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Based on the provided data, 3,3′-Dithiodipropionic acid is not listed as a controlled substance.
How is 3,3′-Dithiodipropionic acid packed, shipped, and exported?
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As a specialist global supplier, Tech Serve Solutions ensures secure and compliant packaging for domestic and international shipments of 3,3′-Dithiodipropionic acid, adhering to all relevant transportation regulations.
How can I request a quote or sample of 3,3′-Dithiodipropionic acid?
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To request a quote or sample, please visit the Tech Serve Solutions website or contact our sales department directly with your specific requirements.
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