(S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-binaphthyl-2,2′-diyl hydrogenphosphate
(S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-binaphthyl-2,2′-diyl hydrogenphosphate, identified by CAS number 874948-63-7 and the molecular formula C50H57O4P, is a chiral phosphoric acid. With a molecular weight of 752.96 g/mol, it serves as a crucial catalyst and reagent in asymmetric synthesis and general chemical synthesis. Its specific stereochemistry makes it valuable for reactions requiring precise chiral control, particularly within the field of chiral catalysts.
- IUPAC
- (11bS)-4-Hydroxy-2,6-bis[2,4,6-tris(1-methylethyl)phenyl]dinaphtho[2,1-d:1′,2′-f]-1,3,2-dioxaphosphepin 4-oxide,(S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-bi-2-naphthol cyclic monophosphate,(S)-TRIP
- Synonyms
- (S)-TRIP(11bS)-4-Hydroxy-2,6-bis[2,4,6-tris(1-methylethyl)phenyl]dinaphtho[2,1-d:1′,2′-f]-1,3,2-dioxaphosphepin 4-oxide(S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-bi-2-naphthol cyclic monophosphate
Asymmetric Synthesis Catalyst
This chiral phosphoric acid acts as a powerful organocatalyst for a variety of enantioselective transformations. It is particularly effective in promoting reactions that require the formation of chiral centres with high stereoselectivity.
Ligand in Chiral Catalysis
As a BINOL-derived phosphoric acid, it functions as a chiral ligand, enabling metal-mediated asymmetric catalysis. Its bulky triisopropylphenyl groups contribute to creating a well-defined chiral environment around the metal centre.
Reagent in Organic Synthesis
Utilised as a key reagent in complex organic synthesis, it facilitates stereospecific reactions crucial for the development of pharmaceuticals and fine chemicals. Its acidic nature and chiral backbone are fundamental to its reactivity.
| Molecular weight | 752.96 |
|---|---|
| Empirical formula | C50H57O4P |
| Assay | ≥97.5% (HPLC) |
| Optical purity | enantiomeric excess: ≥97.5% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Greener Alternative Product Characteristics | Catalysis |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-binaphthyl-2,2′-diyl hydrogenphosphate used for?
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It is primarily used as a chiral catalyst and reagent in asymmetric synthesis and general chemical synthesis, enabling enantioselective transformations.
What are the CAS number and formula for this compound?
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The CAS number is 874948-63-7, and the empirical formula is C50H57O4P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥97.5% (HPLC) and an enantiomeric excess of ≥97.5% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the safety precautions for handling this chemical?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for detailed information.
How is this chemical typically packed, shipped, or exported?
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As a specialist supplier, TSS ensures appropriate packaging and documentation for the safe and compliant shipment and export of chemicals worldwide.
How can I request a sample or quote?
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Please contact our sales team directly through the website or by phone to request a sample or a quotation for this product.
What is the WGK Germany classification for this compound?
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This compound has a WGK Germany classification of 3.
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