4-(Trifluoromethoxy)benzaldehyde
4-(Trifluoromethoxy)benzaldehyde (CAS: 659-28-9, Formula: CF3OC6H4CHO, MW: 190.12) is a valuable organic building block. This trifluoromethoxy-substituted aromatic aldehyde serves as a key intermediate in chemical synthesis, particularly for introducing the 4-(trifluoromethoxy)phenyl moiety into larger molecules. Its reactivity as an aldehyde makes it suitable for various condensation and derivatization reactions, contributing to the development of diverse chemical structures.
- IUPAC
- α,α,α-Trifluoroanisaldehyde
Pharmaceutical Intermediate
Used in the synthesis of complex organic molecules and active pharmaceutical ingredients (APIs). Its unique trifluoromethoxy group can impart desirable pharmacokinetic properties.
Agrochemical Synthesis
Serves as a building block for creating novel agrochemicals, leveraging the electron-withdrawing nature of the trifluoromethoxy substituent.
Materials Science Research
Incorporated into the design of advanced materials, such as liquid crystals or polymers, where the fluorinated group can influence electronic and physical properties.
Organic Synthesis Reagent
A versatile reagent for various organic transformations, including Wittig reactions, Grignard additions, and reductive aminations, facilitating the construction of carbon frameworks.
| Molecular weight | 190.12 |
|---|---|
| Linear formula | CF3OC6H4CHO |
| Assay | 96% |
| Boiling point | 93 °C/27 mmHg(lit.) |
| Density | 1.331 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.458(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 70 °C / 158 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethoxy)benzaldehyde used for?
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4-(Trifluoromethoxy)benzaldehyde is primarily used as a building block and intermediate in organic synthesis for pharmaceuticals, agrochemicals, and materials science research. It allows for the introduction of the 4-(trifluoromethoxy)phenyl group into target molecules.
What is the CAS number and chemical formula for 4-(Trifluoromethoxy)benzaldehyde?
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The CAS number is 659-28-9, and the chemical formula is CF3OC6H4CHO.
What grade and purity does Tech Serve Solutions supply for 4-(Trifluoromethoxy)benzaldehyde?
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Tech Serve Solutions supplies 4-(Trifluoromethoxy)benzaldehyde with a typical assay of 96%. This product is intended for research and chemical synthesis purposes. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the main hazards associated with 4-(Trifluoromethoxy)benzaldehyde?
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4-(Trifluoromethoxy)benzaldehyde is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always handle with appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation.
How is 4-(Trifluoromethoxy)benzaldehyde packed, shipped, and exported?
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We offer various packing options to suit your needs, from laboratory quantities to bulk orders. All shipments comply with international regulations for the transport of chemicals. Tech Serve Solutions is a global supplier and exporter, experienced in international logistics.
How can I request a sample or quote for 4-(Trifluoromethoxy)benzaldehyde?
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You can request a sample or obtain a quote by contacting our sales team through the website or by calling our dedicated customer service line. Please provide your details and the quantity required.
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