4-(Trifluoromethoxy)benzenesulfonyl chloride
4-(Trifluoromethoxy)benzenesulfonyl chloride (CAS 94108-56-2), with the molecular formula CF3OC6H4SO2Cl and a molecular weight of 260.62 g/mol, is a key organic building block. This sulfonyl halide is primarily utilised in chemical synthesis for introducing the 4-(trifluoromethoxy)benzenesulfonyl group into various molecular structures. Its reactivity makes it valuable in the development of novel compounds within the pharmaceutical and agrochemical industries.
Organic Synthesis Reagent
Serves as a crucial reagent in organic synthesis, enabling the formation of sulfonamides and sulfonate esters. It is used to introduce the 4-(trifluoromethoxy)phenylsulfonyl moiety into target molecules.
Pharmaceutical Intermediate
A valuable building block in the synthesis of active pharmaceutical ingredients (APIs). Its unique structural features can contribute to the biological activity and pharmacokinetic properties of drug candidates.
Agrochemical Development
Employed in the development of new agrochemicals, such as herbicides and pesticides. The trifluoromethoxy group can enhance the efficacy and metabolic stability of these compounds.
Material Science Research
Utilised in the research and development of functional materials. The electron-withdrawing nature of the trifluoromethoxy group can influence the electronic and physical properties of polymers and other advanced materials.
| Molecular weight | 260.62 |
|---|---|
| Linear formula | CF3OC6H4SO2Cl |
| Assay | 98% |
| Density | 1.536 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.479(lit.) |
| Vapour pressure | 0.23 psi (20 °C) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethoxy)benzenesulfonyl chloride used for?
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4-(Trifluoromethoxy)benzenesulfonyl chloride (CAS 94108-56-2) is primarily used as a building block in organic synthesis, particularly for introducing the 4-(trifluoromethoxy)phenylsulfonyl group in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals.
What are the CAS number and formula for 4-(Trifluoromethoxy)benzenesulfonyl chloride?
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The CAS number is 94108-56-2 and the molecular formula is CF3OC6H4SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethoxy)benzenesulfonyl chloride with a minimum purity of 98%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This compound is classified as Danger, with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including full-face respirators, gloves, and goggles, is essential. Handle only in a well-ventilated area or under a fume hood. In case of contact, follow emergency procedures as outlined in the Safety Data Sheet.
How is 4-(Trifluoromethoxy)benzenesulfonyl chloride packed and shipped?
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Products are carefully packed to ensure safe transport and export compliance. Specific packaging details can be provided upon request, adhering to all relevant shipping regulations for hazardous materials (UN 3265, Hazard Class 8, Packing Group II).
How can I request a sample or quote?
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To request a sample or a quotation for 4-(Trifluoromethoxy)benzenesulfonyl chloride, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry, referencing the product name and CAS number.
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