Rizatriptan benzoate salt
Rizatriptan benzoate salt (CAS: 145202-66-0; Formula: C15H19N5 · C7H6O2; MW: 391.47 g/mol) is a white to beige powder supplied by TSS. As a selective serotonin 5-HT1B/1D receptor agonist, it plays a crucial role in neuroscience research, particularly in studies involving neurotransmission and GPCR modulation. Its high purity, assaying ≥98% by HPLC, makes it suitable for rigorous laboratory investigations.
- IUPAC
- MK-462,N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate salt
- Synonyms
- N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate saltMK-462

Neuroscience Research
Rizatriptan benzoate salt is utilized in research to investigate serotonin receptor function and its role in neurological processes, including neurotransmission. Its properties as a 5-HT1B/1D agonist make it a valuable tool for studying the mechanisms of neurological signalling pathways.
GPCR Modulation Studies
This compound serves as a modulator in studies focused on G protein-coupled receptors (GPCRs), specifically the serotonin receptors. Researchers employ it to understand signal transduction pathways and the intricate mechanisms of receptor activation and regulation.
Biochemical and Cell Biology Assays
As a biochemical reagent, Rizatriptan benzoate salt can be incorporated into various in vitro assays to assess cellular responses related to serotonin receptor activation. Its defined purity ensures reliable and reproducible experimental outcomes in cell biology investigations.
| Molecular weight | 391.47 |
|---|---|
| Empirical formula | C15H19N5 · C7H6O2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | H2O: ≥5 mg/mL |
| Storage temperature | room temp |

Hazard statements
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P308IF exposed or concerned
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | T |
| Risk statements (R) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Rizatriptan benzoate salt used for?
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Rizatriptan benzoate salt is primarily used in scientific research, particularly in neuroscience, to study serotonin receptor function (5-HT1B/1D) and neurotransmission. It is also employed in GPCR modulation studies and biochemical/cell biology assays.
What are the CAS number and formula for Rizatriptan benzoate salt?
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The CAS number is 145202-66-0, and the empirical formula (Hill notation) is C15H19N5 · C7H6O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Rizatriptan benzoate salt with an assay of ≥98% as determined by HPLC. This product is not classified as USP, BP, EP, or other pharmacopoeial grades and is intended for research purposes only.
How should Rizatriptan benzoate salt be handled and stored?
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Rizatriptan benzoate salt is classified as a Danger substance (GHS08) and poses a hazard to reproduction (H360). It should be stored desiccated at room temperature. Users must follow precautionary statements P201 (Obtain special instructions before use) and P308 + P313 (If exposed or concerned: Get medical advice/attention).
How is Rizatriptan benzoate salt packed and shipped?
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Rizatriptan benzoate salt is typically supplied as a white to beige powder and is stored desiccated at room temperature. TSS exports chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Rizatriptan benzoate salt?
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To request a sample or a quotation for Rizatriptan benzoate salt, please contact the TSS sales team via the website or by phone, providing your contact details and the required quantity.
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