4-(Trifluoromethoxy)anisole
4-(Trifluoromethoxy)anisole (CAS: 710-18-9), with the molecular formula CF3OC6H4OCH3 and a molecular weight of 192.14 g/mol, is a specialised organic building block. This ether derivative serves as a valuable intermediate in various chemical synthesis pathways, particularly in the development of new organic compounds. Its utility extends across research and development sectors, offering unique properties for complex molecular construction.

Organic Synthesis Intermediate
Utilised as a building block in the synthesis of more complex organic molecules. It provides a trifluoromethoxy and an anisole moiety for incorporation into target structures.
Pharmaceutical Research
Serves as a precursor or intermediate in the research and development of novel pharmaceutical agents. The trifluoromethoxy group can influence pharmacokinetic properties.
Materials Science
Investigated for potential applications in the development of advanced materials due to its specific functional groups and chemical properties.
| Molecular weight | 192.14 |
|---|---|
| Linear formula | CF3OC6H4OCH3 |
| Assay | 98% |
| Boiling point | 164 °C(lit.) |
| Density | 1.266 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.432(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 23-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethoxy)anisole used for?
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4-(Trifluoromethoxy)anisole is primarily used as a building block in organic synthesis and for research and development in areas such as pharmaceutical discovery and materials science.
What are the CAS number and molecular formula for 4-(Trifluoromethoxy)anisole?
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The CAS number for 4-(Trifluoromethoxy)anisole is 710-18-9, and its molecular formula is CF3OC6H4OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethoxy)anisole with an assay of 98%. This is a technical/research grade product, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety hazards associated with 4-(Trifluoromethoxy)anisole?
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4-(Trifluoromethoxy)anisole is a flammable liquid and vapour (H226). It is harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). It also causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be used.
Is 4-(Trifluoromethoxy)anisole a controlled substance?
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The provided data does not indicate that 4-(Trifluoromethoxy)anisole is a controlled substance.
How is 4-(Trifluoromethoxy)anisole packed and exported?
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As a global supplier, Tech Serve Solutions exports chemicals according to international shipping regulations. For specific packing details, please contact our sales team.
How can I request a quote or sample for 4-(Trifluoromethoxy)anisole?
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To request a quote or sample, please use the 'Request a Quote' or 'Request Sample' buttons on our product page, or contact our customer service department directly.
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