4-(Trifluoromethoxy)benzylboronic acid pinacol ester

CAS 872038-32-9C14H18BF3O3Chemical Synthesis

4-(Trifluoromethoxy)benzylboronic acid pinacol ester (CAS: 872038-32-9; Formula: C14H18BF3O3) is a high-purity organoboron compound with a molecular weight of 302.10 g/mol. This ester derivative of boronic acid is a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its trifluoromethoxybenzyl moiety makes it suitable for introducing specific functional groups into complex molecules, aiding in the development of novel materials and pharmaceuticals.

IUPAC: 4,4,5,5-Tetramethyl-2-[(4-trifluoromethoxy)benzyl]-1,3,2-dioxaborolane
Synonyms: 4,4,5,5-Tetramethyl-2-[(4-trifluoromethoxy)benzyl]-1,3,2-dioxaborolane

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4-(Trifluoromethoxy)benzylboronic acid pinacol ester (C14H18BF3O3) — chemical structure, CAS 872038-32-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Alkyl Boronate EstersBoronate EstersChemical SynthesisOrganometallic Reagents

01 /Applications

Suzuki-Miyaura Cross-Coupling Reactions

Utilised as a coupling partner in Suzuki-Miyaura reactions to form new carbon-carbon bonds. This enables the synthesis of complex biaryl compounds and other substituted aromatic systems.

Pharmaceutical Intermediate Synthesis

Serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). The trifluoromethoxy group can impart desirable pharmacokinetic properties to drug candidates.

Materials Science Research

Incorporated into the design and synthesis of advanced materials, such as organic light-emitting diodes (OLEDs) or functional polymers, where specific electronic or optical properties are required.

Agrochemical Development

A building block for the creation of novel agrochemicals, contributing to the development of new pesticides or herbicides with tailored efficacy and environmental profiles.

02 /Properties

Molecular weight	302.10
Empirical formula	C14H18BF3O3
Assay	97%
Boiling point	100 °C/0.2 mmHg
Density	1.139 g/mL at 25 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US)
Flash point	105 °C / 221 °F
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

872038-32-9

MDL number

MFCD08276838

PubChem substance

24884608

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-(Trifluoromethoxy)benzylboronic acid pinacol ester used for?

This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the construction of complex molecules in pharmaceutical, materials science, and agrochemical research and development.

What are the CAS number and formula for this product?

The CAS number is 872038-32-9 and the empirical formula (Hill notation) is C14H18BF3O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product at a minimum assay of 97%. It is supplied for research and laboratory use and is not represented as USP, BP, EP, or any pharmacopoeia grade.

What are the safety and handling recommendations?

This compound is combustible and requires appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (half-mask respirator EU/US, multi-purpose combination cartridge US). Handle in a well-ventilated area, away from ignition sources. Refer to the Safety Data Sheet (SDS) for comprehensive handling and hazard information.

How is this chemical packaged and shipped?

This chemical is available in various pack sizes suitable for laboratory use and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.

How can I request a sample or a quote?

You can request a sample or a quote by contacting our sales team directly through the Tech Serve Solutions website or by calling us. Please reference the product name and CAS number.