NBI 27914
NBI 27914 (CAS: 184241-44-9) is a chemical compound with the formula C18H20Cl4N4 and a molecular weight of 434.19 g/mol. Supplied as a white solid, it is a bioactive small molecule primarily utilised in cell biology and neuroscience research. Its applications often involve investigating cell signalling pathways and neuropeptide functions, making it a valuable reagent for advanced laboratory studies in these fields.
- IUPAC
- 5-Chloro-4-(N-(cyclopropyl)methyl-N-propylamino)-2-methyl-6-(2,4,6-trichlorophenyl)aminopyridine

Cell Biology Research
NBI 27914 is employed in cellular and molecular biology research to investigate cell signalling pathways and cellular responses. Its properties make it suitable for studies on the mechanisms of cellular communication.
Neuroscience Investigations
This compound serves as a tool in neuroscience research, particularly for studies involving neuropeptides and their receptors. It aids in understanding neuronal function and related signalling cascades.
CRF Pathway Studies
NBI 27914 is associated with research into the Corticotropin-Releasing Factor (CRF) pathway. It can be used to explore the physiological and behavioural effects mediated by this system.
| Molecular weight | 434.19 |
|---|---|
| Empirical formula | C18H20Cl4N4 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >20 mg/mL at 60 °CH2O: insoluble |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CRHR1(1394) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is NBI 27914 used for?
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NBI 27914 is used in research settings, particularly within cell biology and neuroscience, to study cell signalling pathways, neuropeptides, and related biological functions.
What is the CAS number and molecular formula for NBI 27914?
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The CAS number for NBI 27914 is 184241-44-9, and its molecular formula is C18H20Cl4N4.
What grade and purity does Tech Serve Solutions supply for NBI 27914?
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Tech Serve Solutions supplies NBI 27914 with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should NBI 27914 be handled and stored?
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NBI 27914 is classified as a warning substance with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). It should be handled with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Store in a refrigerator at 2-8°C.
Is NBI 27914 available for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including NBI 27914, which can be shipped worldwide.
How can I request a quote or sample of NBI 27914?
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To request a quote or a sample of NBI 27914, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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