NBQX disodium salt hydrate
NBQX disodium salt hydrate (CAS: 118876-58-7) is a selective antagonist of AMPA and kainate subtypes of ionotropic glutamate receptors. With the molecular formula C12H6N4Na2O6S · xH2O and a molecular weight of 380.24 (anhydrous basis), this lyophilized solid is primarily used in neuroscience research to modulate excitatory neurotransmission. Its role in cellular signaling makes it a valuable tool for studying neurological processes.
- IUPAC
- 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt hydrate,FG 9202 disodium salt hydrate
- Synonyms
- 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt hydrateFG 9202 disodium salt hydrate
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Neuroscience Research Tool
NBQX disodium salt hydrate serves as a critical reagent for investigating the function of AMPA and kainate receptors in the central nervous system. It aids in understanding synaptic plasticity, neuronal excitability, and the mechanisms underlying neurological disorders.
Cell Signaling Studies
This compound is employed to study the intricate pathways of excitatory amino acid neurotransmission. Researchers utilise it to dissect cellular responses mediated by ionotropic glutamate receptors, contributing to the broader field of cell signaling.
Ligand-Gated Ion Channel Modulator
As a selective modulator of ligand-gated ion channels, NBQX disodium salt hydrate is instrumental in electrophysiological studies. It allows for precise control over receptor activation, facilitating detailed analysis of channel kinetics and pharmacology.
| Molecular weight | 380.24 (anhydrous basis) |
|---|---|
| Empirical formula | C12H6N4Na2O6S · xH2O |
| Assay | ≥98% (HPLC) |
| Form | lyophilized solid |
| Colour | , brown to dark red-brown |
| Solubility | H2O: >10 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is NBQX disodium salt hydrate used for?
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NBQX disodium salt hydrate is primarily used as a selective antagonist of AMPA and kainate receptors in neuroscience research to study excitatory neurotransmission and related cellular signaling pathways.
What is the CAS number and molecular formula for NBQX disodium salt hydrate?
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The CAS number for the free acid form is 118876-58-7. The empirical formula for the disodium salt hydrate is C12H6N4Na2O6S · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies NBQX disodium salt hydrate with an assay of ≥98% determined by HPLC. This product is intended for research purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should NBQX disodium salt hydrate be handled and stored?
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NBQX disodium salt hydrate is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Store desiccated at 2-8°C.
Is NBQX disodium salt hydrate a controlled substance?
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The provided data does not indicate that NBQX disodium salt hydrate is a controlled substance.
How can I request a quote or sample for NBQX disodium salt hydrate?
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Please contact our sales team via the website or by phone to request a quote or inquire about sample availability for NBQX disodium salt hydrate.
How is this chemical packed and shipped?
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NBQX disodium salt hydrate is supplied as a lyophilized solid and is shipped according to standard chemical transport regulations, ensuring its stability and integrity.
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