4-Methoxy-TEMPO
4-Methoxy-TEMPO (CAS: 95407-69-5), with the molecular formula C10H20NO2 and a molecular weight of 186.27 g/mol, is a stable nitroxyl radical. It functions as a versatile reagent in organic synthesis, particularly as an oxidation catalyst. Its applications span the synthesis of fine chemicals and pharmaceutical intermediates, leveraging its controlled radical nature for selective chemical transformations.
- IUPAC
- 4-Methoxy-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical
- Synonyms
- 4-Methoxy-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical

Catalyst in Organic Synthesis
4-Methoxy-TEMPO serves as an effective catalyst for various oxidation reactions, including the selective oxidation of alcohols to aldehydes and ketones. Its ability to participate in controlled radical processes makes it valuable for complex synthetic pathways.
Radical Chemistry Research
As a stable radical, this compound is widely employed in academic and industrial research settings to study radical mechanisms and develop new synthetic methodologies. It is a key reagent in exploring electron transfer processes.
Synthesis of Pharmaceutical Intermediates
The compound finds application in the multi-step synthesis of active pharmaceutical ingredients (APIs) and their precursors. Its catalytic properties aid in achieving high yields and selectivities in crucial synthetic steps.
| Molecular weight | 186.27 |
|---|---|
| Empirical formula | C10H20NO2 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 40.5-44 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxy-TEMPO used for?
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4-Methoxy-TEMPO is primarily used as a catalyst in organic synthesis, particularly for selective oxidation reactions, and in the study of radical chemistry.
What are the CAS number and formula for 4-Methoxy-TEMPO?
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The CAS number for 4-Methoxy-TEMPO is 95407-69-5, and its molecular formula is C10H20NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methoxy-TEMPO with an assay of 97%. This product is intended for research and synthesis purposes and is not supplied as USP, BP, or EP grade.
What are the safety and handling considerations for 4-Methoxy-TEMPO?
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4-Methoxy-TEMPO is classified as a warning substance, with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). It requires appropriate personal protective equipment such as a dust mask (N95), eyeshields, and gloves. Handle in a well-ventilated area.
How is 4-Methoxy-TEMPO shipped and exported?
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Tech Serve Solutions, as a global supplier and exporter, can provide 4-Methoxy-TEMPO to various international destinations, adhering to all relevant shipping and export regulations for chemical products.
How can I request a sample or quote for 4-Methoxy-TEMPO?
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To request a sample or a detailed quote for 4-Methoxy-TEMPO, please use the contact form on our website or reach out to our sales department directly.
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