NBQX hydrate
NBQX hydrate (CAS: 118876-58-7) is a chemical compound with the formula C12H8N4O6S · xH2O and a molecular weight of 336.28 g/mol (anhydrous basis). This yellow powder is primarily utilised as a research chemical. It functions as a selective antagonist for AMPA and kainate receptors, making it valuable in neuroscience research to investigate glutamatergic neurotransmission and its role in various physiological and pathological processes.
- IUPAC
- 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide hydrate,FG 9202
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Neuroscience Research
NBQX hydrate serves as a vital tool for studying the roles of AMPA and kainate receptors in the central nervous system. It aids in understanding excitatory neurotransmission and its implications in neurological disorders.
Pharmacological Tool
As a selective antagonist, NBQX hydrate is used in pharmacological investigations to probe the function of specific ionotropic glutamate receptors. This helps in differentiating receptor contributions in complex neural circuits.
Cellular Signaling Studies
This compound can be employed to investigate cellular signaling pathways modulated by glutamate receptors. Its use helps elucidate downstream effects and regulatory mechanisms within neurons and other excitable cells.
| Molecular weight | 336.28 (anhydrous basis) |
|---|---|
| Empirical formula | C12H8N4O6S · xH2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | yellow |
| Solubility | methanol: soluble0.25 mg/mL45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble0.5 mg/mLDMSO: soluble4 mg/mLH2O: insoluble |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is NBQX hydrate used for?
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NBQX hydrate is primarily used in neuroscience research as a selective antagonist for AMPA and kainate receptors to study excitatory neurotransmission and its role in neurological processes.
What are the CAS number and formula for NBQX hydrate?
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The CAS number for the anhydrous form is 118876-58-7, and the formula is C12H8N4O6S · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies NBQX hydrate with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for NBQX hydrate?
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NBQX hydrate is a Warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95, eyeshields, and gloves. Handle in a well-ventilated area.
How is NBQX hydrate packed, shipped, and exported?
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NBQX hydrate is carefully packed in compliance with all relevant shipping regulations for chemicals. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a sample or quote for NBQX hydrate?
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To request a sample or a quote for NBQX hydrate, please contact our sales team through the website or by phone.
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