(2R)-N-[(1R,2R)-2-Hydroxy-1,2-diphenylethyl]-2-pyrrolidinecarboxamide
(2R)-N-[(1R,2R)-2-Hydroxy-1,2-diphenylethyl]-2-pyrrolidinecarboxamide (CAS 948594-97-6) is a chiral organic compound with the molecular formula C19H22N2O2. As a proline-based organocatalyst, it is primarily employed in asymmetric synthesis and chemical transformations requiring precise stereochemical control. Its structure facilitates enantioselective reactions, making it valuable in the development of complex molecules and pharmaceutical intermediates. Tech Serve Solutions supplies this reagent with a minimum assay of 99.0%.
- IUPAC
- (2R,1′R, 2′R)-Pyrrolidine-2-carboxylic acid (2-hydroxy-1,2-diphenyl-ethyl)amide
- Synonyms
- 948594-97-6C19H22N2O2(2R,1′R, 2′R)-Pyrrolidine-2-carboxylic acid (2-hydroxy-1,2-diphenyl-ethyl)amide
![(2R)-N-[(1R,2R)-2-Hydroxy-1,2-diphenylethyl]-2-pyrrolidinecarboxamide (C19H22N2O2) — chemical structure, CAS 948594-97-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F948594-97-6.png&w=3840&q=75)
Asymmetric Synthesis
This compound serves as a chiral catalyst or ligand in asymmetric synthesis, enabling the selective formation of one enantiomer over the other in chemical reactions. It is particularly useful for creating complex chiral molecules with high stereochemical purity.
Chiral Ligand Development
Its specific stereochemistry makes it a valuable building block or component in the design and synthesis of novel chiral ligands for transition metal catalysis. This aids in the development of new catalytic systems for enantioselective transformations.
Pharmaceutical Intermediate Synthesis
The ability to control stereochemistry is critical in pharmaceutical development, and this reagent can be utilised in the synthesis pathways of chiral active pharmaceutical ingredients (APIs) or their key intermediates.
Organocatalysis Research
As a proline-derived organocatalyst, it is employed in academic and industrial research to explore new catalytic methodologies and reaction pathways that leverage the principles of organocatalysis.
| Empirical formula | C19H22N2O2 |
|---|---|
| Assay | ≥99.0% (HPLC) |
| Optical activity | [α]/D +25±2°, c = 2 in ethanol |
| Storage temperature | 2-8°C |
| Melting point | 127-131 °C |
Hazard statements
- H301Toxic if swallowed
- H331Toxic if inhaled
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 23/25-50 |
| Safety statements (S) | 45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2R)-N-[(1R,2R)-2-Hydroxy-1,2-diphenylethyl]-2-pyrrolidinecarboxamide used for?
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(2R)-N-[(1R,2R)-2-Hydroxy-1,2-diphenylethyl]-2-pyrrolidinecarboxamide is primarily used in asymmetric synthesis and organocatalysis, serving as a chiral catalyst or ligand for enantioselective reactions and in the development of chiral molecules.
What is the CAS number and molecular formula?
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The CAS number is 948594-97-6 and the molecular formula is C19H22N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2R)-N-[(1R,2R)-2-Hydroxy-1,2-diphenylethyl]-2-pyrrolidinecarboxamide with a minimum assay of ≥99.0% (HPLC). This product is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should this chemical be handled and stored?
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This compound is classified as toxic if inhaled and acutely toxic if swallowed, and is very toxic to aquatic life. It requires careful handling with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges. Store at 2-8°C.
Is this product controlled or scheduled?
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The provided safety data does not indicate that this specific compound is a controlled or scheduled substance.
How can I request a sample or quote?
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To request a sample or a quotation for (2R)-N-[(1R,2R)-2-Hydroxy-1,2-diphenylethyl]-2-pyrrolidinecarboxamide, please contact our sales department through the website or by phone.
How is this chemical typically shipped or exported?
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As per UN 2811, 6.1/PG 3 classification, this chemical is shipped as a toxic solid, organic, n.o.s., requiring appropriate hazard labelling and documentation for domestic and international export.
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