Boc-Met(O2)-OH
N-Boc-L-methionine sulfone (CAS 60280-45-7) is a protected amino acid derivative with the molecular formula C10H19NO6S and a molecular weight of 281.33 g/mol. This compound is valuable in chemical synthesis and peptide chemistry. It is a key intermediate for introducing modified methionine residues into peptides, particularly where oxidation of the sulfur atom is desired or needs to be prevented.
- IUPAC
- Boc-L-methionine sulfone
- Synonyms
- Boc-L-methionine sulfone
Peptide Synthesis
Used as a building block in solid-phase or solution-phase peptide synthesis to incorporate a protected, oxidised methionine analogue. This allows for the creation of peptides with specific structural or functional modifications.
Chemical Biology
Applied in research to study the roles of methionine oxidation in biological systems or to design peptides with altered properties. Its unique structure can probe specific interactions or resistance to oxidative stress.
Organic Synthesis
Serves as a versatile intermediate in the synthesis of complex organic molecules and pharmaceutical candidates. The Boc protecting group and the sulfone moiety offer distinct reactivity for further transformations.
| Molecular weight | 281.33 |
|---|---|
| Empirical formula | C10H19NO6S |
| Assay | ≥96.0% (TLC) |
| Optical activity | [α]20/D −13.5±1°, c = 1% in DMF |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-L-methionine sulfone used for?
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N-Boc-L-methionine sulfone is primarily used in peptide synthesis as a protected amino acid building block for incorporating oxidised methionine analogues. It also finds applications in chemical biology and general organic synthesis.
What are the CAS number and formula for N-Boc-L-methionine sulfone?
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The CAS number is 60280-45-7 and the empirical formula (Hill notation) is C10H19NO6S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-L-methionine sulfone with an assay of ≥96.0% (determined by TLC). We do not represent this product as USP, BP, or EP grade, and it is supplied for research and development purposes.
How should N-Boc-L-methionine sulfone be handled?
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When handling, appropriate personal protective equipment including eyeshields and gloves should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound has a WGK rating of 3 in Germany.
Is N-Boc-L-methionine sulfone a controlled substance?
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Based on the provided data, N-Boc-L-methionine sulfone is not indicated as a controlled substance.
How is N-Boc-L-methionine sulfone shipped?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents. Specific shipping details and compliance with export regulations will be provided upon request.
How can I request a quote or sample?
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To request a quote or a sample of N-Boc-L-methionine sulfone, please contact our sales department through the website or by phone.
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