Boc-Lys(Fmoc)-OH
Nα-Boc-Nε-Fmoc-L-lysine (CAS: 84624-27-1), with the molecular formula C26H32N2O6 and a molecular weight of 468.54 g/mol, is a protected amino acid derivative. It is widely employed in peptide synthesis and chemical biology due to its dual protection strategy, allowing for selective deprotection. This compound is essential for building complex peptides and modified amino acid structures for research and development purposes.
- IUPAC
- Nα-Boc-Nε-Fmoc-L-lysine

Peptide Synthesis
This dual-protected lysine derivative is a crucial building block in solid-phase and solution-phase peptide synthesis. The Boc and Fmoc protecting groups enable orthogonal deprotection strategies, facilitating the controlled assembly of complex peptide sequences.
Chemical Biology Research
It serves as a versatile tool for introducing lysine residues with specific modifications into peptides and proteins. This is valuable for studying protein function, developing biochemical probes, and creating targeted drug delivery systems.
Organic Synthesis
Beyond peptide chemistry, Nα-Boc-Nε-Fmoc-L-lysine can be utilised in various organic synthesis routes requiring a protected lysine moiety. Its defined protecting groups allow for selective reactions at other parts of the molecule.
| Molecular weight | 468.54 |
|---|---|
| Empirical formula | C26H32N2O6 |
| Assay | ≥99.0% (sum of enantiomers, TLC) |
| Optical activity | [α]20/D +3.3±0.5°, c = 1% in ethyl acetate |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Boc-Nε-Fmoc-L-lysine used for?
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Nα-Boc-Nε-Fmoc-L-lysine is primarily used as a protected amino acid building block in peptide synthesis and chemical biology research for the construction of complex peptide sequences and modified amino acid structures.
What is the CAS number and formula for Nα-Boc-Nε-Fmoc-L-lysine?
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The CAS number is 84624-27-1, and the empirical formula (Hill notation) is C26H32N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nα-Boc-Nε-Fmoc-L-lysine with an assay of ≥99.0% (sum of enantiomers, TLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for this product?
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Users should wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used when exposure is possible. The product is classified under WGK Germany 3, indicating a high hazard to water.
How is this chemical typically shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product is typically stored at 2-8°C and is carefully packaged and exported according to international shipping regulations for chemical substances.
How can I request a sample or a quote for Nα-Boc-Nε-Fmoc-L-lysine?
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To request a sample or a quote, please contact our sales department through the TSS website or direct email, providing your specific requirements and shipping details.
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