Boc-Leu-OSu
N-(tert-Butoxycarbonyl)-L-leucine N-hydroxysuccinimide ester (CAS: 3392-09-4), with the empirical formula C15H24N2O6 and a molecular weight of 328.36 g/mol, is a key reagent in peptide synthesis. This activated ester of Boc-protected leucine facilitates the formation of peptide bonds under mild conditions. It is primarily utilised in chemical synthesis and research involving peptide chemistry and chemical biology.
- IUPAC
- N-(tert-Butoxycarbonyl)-L-leucine N-hydroxysuccinimide ester,Boc-L-leucine hydroxysuccinimide ester
- Synonyms
- N-(tert-Butoxycarbonyl)-L-leucine N-hydroxysuccinimide esterBoc-L-leucine hydroxysuccinimide ester

Peptide Synthesis Reagent
Serves as an activated ester of N-Boc-L-leucine, enabling efficient coupling reactions for the formation of peptide bonds in solid-phase or solution-phase synthesis. It is crucial for constructing peptides with specific sequences.
Chemical Biology Research
Used in the construction of modified peptides and peptidomimetics for investigating biological pathways and protein interactions. Its defined structure aids in creating probes for biochemical studies.
Amino Acid Derivative
As a protected amino acid derivative, it is a valuable building block in organic synthesis for creating complex molecules containing leucine residues.
| Molecular weight | 328.36 |
|---|---|
| Empirical formula | C15H24N2O6 |
| Assay | ≥99.0% ((TLC)) |
| Optical activity | [α]20/D −43.5±1°, c = 1% in dioxane |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Leu-OSu used for?
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Boc-Leu-OSu (CAS: 3392-09-4) is primarily used as an activated N-hydroxysuccinimide ester in peptide synthesis to couple N-Boc-L-leucine residues into peptide chains.
What is the CAS number and formula for Boc-Leu-OSu?
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The CAS number for Boc-Leu-OSu is 3392-09-4 and its empirical formula is C15H24N2O6.
What grade and purity does Tech Serve Solutions supply for Boc-Leu-OSu?
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Tech Serve Solutions supplies Boc-Leu-OSu with an assay of ≥99.0% (TLC). This product is intended for research and chemical synthesis and is not supplied as USP, BP, or EP grade.
How should Boc-Leu-OSu be handled and stored?
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Handle Boc-Leu-OSu with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at -20°C.
Is Boc-Leu-OSu a controlled substance?
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The provided data does not indicate that Boc-Leu-OSu (CAS: 3392-09-4) is a controlled substance.
How is Boc-Leu-OSu packed and exported by TSS?
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Tech Serve Solutions carefully packs and exports chemicals globally, adhering to all relevant shipping regulations for international transport.
How can I request a sample or quote for Boc-Leu-OSu?
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Please contact our sales team directly via our website or listed phone number to request a sample or a detailed quotation for Boc-Leu-OSu.
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