Boc-Leu-OH

CAS 13139-15-6(CH3)2CHCH2CH(COOH)NHCOOC(CH3)3Chemical Synthesis

Boc-L-leucine (CAS: 13139-15-6) is a protected amino acid derivative with the linear formula (CH₃)₂CHCH₂CH(COOH)NHCOOC(CH₃)₃ and a molecular weight of 231.29 g/mol. It is a key intermediate in peptide synthesis and organic chemistry. This compound, typically supplied at ≥99.0% purity by Tech Serve Solutions, serves as a valuable building block in the creation of complex molecules and has been utilised in the synthesis of specific cytotoxins for research applications.

IUPAC: Boc-L-leucine
Synonyms: N-(tert-Butoxycarbonyl)-L-leucineBoc-Leu-OH(S)-2-((tert-Butoxycarbonyl)amino)-4-methylpentanoic acid

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Boc-Leu-OH ((CH3)2CHCH2CH(COOH)NHCOOC(CH3)3) — chemical structure, CAS 13139-15-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisLeucinePeptide Chemistry

01 /Applications

Peptide Synthesis

Boc-L-leucine is a widely used N-protected amino acid essential for solid-phase and solution-phase peptide synthesis. The tert-butyloxycarbonyl (Boc) protecting group facilitates controlled peptide chain elongation.

Organic Synthesis Intermediate

This derivative acts as a versatile building block in organic synthesis, enabling the introduction of the leucine side chain into various molecular architectures. Its protected nature allows for selective chemical transformations.

Chemical Biology Research

Boc-L-leucine has been employed in research for the synthesis of complex biomolecules and probes. For example, it was utilised in the preparation of the cytotoxin PM-94128 for scientific investigation.

02 /Properties

Molecular weight	231.29
Linear formula	(CH3)2CHCH2CH(COOH)NHCOOC(CH3)3
Assay	≥99.0% (HPLC)
Optical activity	[α]20/D −25±0.5°, c = 2% in acetic acid
Application	Boc-Leu-OH (Boc-L-leucine) was used in the synthesis of a potent cytotoxin, PM-941281.
Melting point	85-90 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

13139-15-6

MDL number

MFCD00066067

Beilstein registry

1711814

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-L-leucine used for?

Boc-L-leucine is primarily used as an intermediate in peptide synthesis and general organic synthesis. It has also been used in the preparation of specific research compounds, such as the cytotoxin PM-94128.

What are the CAS number and molecular formula for Boc-L-leucine?

The CAS number for Boc-L-leucine is 13139-15-6. Its linear formula is (CH₃)₂CHCH₂CH(COOH)NHCOOC(CH₃)₃.

What grade and purity does Tech Serve Solutions supply for Boc-L-leucine?

Tech Serve Solutions supplies Boc-L-leucine with an assay of ≥99.0% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.

What are the safety considerations when handling Boc-L-leucine?

Handle Boc-L-leucine with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 3.

How is Boc-L-leucine packed and shipped?

Boc-L-leucine is carefully packed to ensure product integrity during transit. Tech Serve Solutions is a global supplier and exporter, adhering to international shipping regulations for chemical products.