Boc-Leu-ONp
Boc-Leu-ONp (CAS 3350-19-4), with the molecular formula C17H24N2O6 and a molecular weight of 352.38, is a protected amino acid derivative. This compound is primarily utilised in chemical synthesis, particularly in peptide chemistry and chemical biology. It serves as a valuable reagent for introducing the Boc-protected leucine residue into peptides or other organic molecules. Tech Serve Solutions supplies this chemical for research and development purposes.
- IUPAC
- Boc-L-leucine 4-nitrophenyl ester

Peptide Synthesis
Boc-Leu-ONp is employed as an activated amino acid derivative in solid-phase and solution-phase peptide synthesis. The 4-nitrophenyl ester group facilitates coupling reactions, enabling the efficient incorporation of Boc-protected leucine into growing peptide chains.
Chemical Biology Research
This compound can be used in chemical biology to synthesise modified peptides or peptidomimetics. Its controlled reactivity allows for specific modifications and labelling in biological systems or for studying protein-ligand interactions.
Organic Synthesis Intermediate
As a functionalized leucine derivative, Boc-Leu-ONp serves as a versatile intermediate in the synthesis of complex organic molecules. It is useful in constructing chiral building blocks and target compounds in medicinal chemistry.
| Molecular weight | 352.38 |
|---|---|
| Empirical formula | C17H24N2O6 |
| Assay | ≥96.0% (TLC) |
| Storage temperature | 2-8°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Leu-ONp used for?
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Boc-Leu-ONp is primarily used as a reagent in peptide synthesis, chemical biology research, and general organic synthesis as a protected leucine derivative.
What is the CAS number and molecular formula for Boc-Leu-ONp?
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The CAS number is 3350-19-4, and the molecular formula is C17H24N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Leu-ONp with an assay of ≥96.0% (TLC). This is a research-grade chemical and is not supplied as USP, BP, or EP grade.
How should Boc-Leu-ONp be handled and stored?
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Boc-Leu-ONp should be stored at 2-8°C. Refer to the Safety Data Sheet (SDS) for detailed handling, safety precautions, and hazard information, as it is classified under WGK 3 in Germany.
Is Boc-Leu-ONp a controlled substance?
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The provided data does not indicate that Boc-Leu-ONp is a controlled substance.
How are chemicals like Boc-Leu-ONp packed, shipped, and exported by TSS?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, ensuring appropriate packaging and adherence to international shipping regulations for safe and compliant delivery.
How can I request a sample or quote for Boc-Leu-ONp?
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To request a sample or quote for Boc-Leu-ONp, please contact the Tech Serve Solutions sales team through the provided contact channels on our website.
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