Boc-L-leucinol

CAS 82010-31-9(CH3)2CHCH2CH[NHCO2C(CH3)3]CH2OHChemical Synthesis

Boc-L-leucinol (CAS: 82010-31-9) is a protected amino alcohol with the molecular formula (CH3)2CHCH2CH[NHCO2C(CH3)3]CH2OH and a molecular weight of 217.31 g/mol. This chemical serves as a valuable chiral building block in organic synthesis, particularly for the preparation of enantiomerically pure amines and amino acids. Its protected nature facilitates controlled reactions, making it a key intermediate in complex molecule synthesis.

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Boc-L-leucinol ((CH3)2CHCH2CH[NHCO2C(CH3)3]CH2OH) — chemical structure, CAS 82010-31-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesAmino AlcoholsChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Synthesis of Chiral Amines

Boc-L-leucinol is utilised as a precursor for the synthesis of enantiomerically pure α-methyl amines, which are important substructures in pharmaceuticals and chiral auxiliaries.

Preparation of Homo-β-Amino Acids

This compound is a starting material for the synthesis of enantiopure homo-β-amino acids, a class of non-proteinogenic amino acids with diverse biological activities and applications in peptide chemistry.

N-Protected α-Amino Aldehyde Synthesis

It serves as a precursor in the synthesis of N-protected α-amino aldehydes, versatile intermediates used in the construction of complex organic molecules.

Amicoumacin C Total Synthesis

Boc-L-leucinol has been employed in the total synthesis of amicoumacin C, a natural product exhibiting gastro-protective properties, highlighting its role in complex natural product synthesis.

02 /Properties

Molecular weight	217.31
Linear formula	(CH3)2CHCH2CH[NHCO2C(CH3)3]CH2OH
Assay	95%
Optical activity	[α]23/D −27°, c = 2 in methanol
Application	Precursor to enantiomerically pure α-methyl amines.1 Starting material for the synthesis of enantiopure homo-β-amino acids2,3 and N-protected α-amino aldehydes.4 Used in the total synthesis of the gastro-protective amicoumacin C.5

03 /Safety & handling

Protective equipment	Eyeshields, Gloves
Flash point	>110 °C / >230 °F
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

82010-31-9

MDL number

MFCD00076950

Beilstein registry

4178460

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-L-leucinol used for?

Boc-L-leucinol is used as a precursor for enantiomerically pure α-methyl amines, a starting material for enantiopure homo-β-amino acids and N-protected α-amino aldehydes, and in the total synthesis of amicoumacin C.

What is the CAS number and formula for Boc-L-leucinol?

The CAS number for Boc-L-leucinol is 82010-31-9, and its linear formula is (CH3)2CHCH2CH[NHCO2C(CH3)3]CH2OH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Boc-L-leucinol with a minimum assay of 95%. TSS does not represent this product as USP, BP, EP or any pharmacopoeia grade.

How should Boc-L-leucinol be handled and stored?

Handle Boc-L-leucinol with appropriate personal protective equipment, including eyeshields and gloves. Store in a cool, dry place. It has a flash point above 110 °C (230 °F).