N-Benzyl-2-bromo-N-phenylbutanamide
N-Benzyl-2-bromo-N-phenylbutanamide (CAS: 851073-30-8) is a chemical compound with the molecular formula C17H18BrNO and a molecular weight of 332.23 g/mol. This brominated amide serves as a valuable building block in organic synthesis, particularly in asymmetric catalysis. It is notably employed in Ni-pybox catalysed asymmetric Negishi couplings, facilitating the formation of new carbon-carbon bonds in a stereoselective manner.
Asymmetric Negishi Couplings
N-Benzyl-2-bromo-N-phenylbutanamide is utilised as a key substrate in nickel-pybox catalysed asymmetric Negishi couplings. This application allows for the stereoselective formation of carbon-carbon bonds, a crucial step in the synthesis of complex organic molecules.
Organic Synthesis Building Block
As a versatile building block, this compound provides a functionalised amide scaffold for constructing more elaborate molecular architectures. Its bromo-amide functionality enables various synthetic transformations.
Catalysis Research
The compound's role in asymmetric catalysis makes it relevant for research into developing novel catalytic systems and methodologies for chiral synthesis.
| Molecular weight | 332.23 |
|---|---|
| Empirical formula | C17H18BrNO |
| Assay | 97% |
| Application | Used in Ni-pybox catalyzed asymmetric Negishi couplings.1 |
| Melting point | 44-50 °C |
Hazard statements
- H315Causes skin irritation
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P501Dispose of contents and container per local regulations
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Benzyl-2-bromo-N-phenylbutanamide used for?
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N-Benzyl-2-bromo-N-phenylbutanamide is primarily used as a building block in organic synthesis, specifically in Ni-pybox catalysed asymmetric Negishi couplings for stereoselective carbon-carbon bond formation.
What are the CAS number and formula for N-Benzyl-2-bromo-N-phenylbutanamide?
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The CAS number is 851073-30-8, and its empirical formula (Hill notation) is C17H18BrNO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Benzyl-2-bromo-N-phenylbutanamide with an assay of 97%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for this chemical?
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This compound is classified with GHS07 and GHS09 symbols and a Warning signal word. It carries hazard statements H315 (Causes skin irritation) and H410 (Very toxic to aquatic life with long lasting effects). Recommended personal protective equipment includes a dust mask (N95 type), eyeshields, and gloves. Handle in a well-ventilated area and avoid release to the environment (P273).
How is N-Benzyl-2-bromo-N-phenylbutanamide packed and shipped?
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N-Benzyl-2-bromo-N-phenylbutanamide is classified as UN 3077, 9/PGIII. It is suitable for shipping and export, following appropriate regulations for environmentally hazardous substances.
How can I request a quote or sample?
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To request a quote or a sample of N-Benzyl-2-bromo-N-phenylbutanamide, please visit the Tech Serve Solutions website or contact our sales department directly.
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