Fluoroacetic acid
Fluoroacetic acid (CAS: 144-49-0, C2H3FO2) is a highly toxic organofluorine compound and a potent metabolic inhibitor. It acts by converting to fluorocitrate, which strongly inhibits the enzyme aconitase in the Krebs cycle. This leads to a cascade of cellular disruptions. While its extreme toxicity limits direct applications, it serves as a critical intermediate in the synthesis of specific fluorinated organic compounds and pharmaceuticals. Handle with extreme caution due to its severe hazards.
Chemical Synthesis Intermediate
Fluoroacetic acid serves as a building block in the synthesis of more complex fluorinated organic molecules. Its reactive nature allows for the introduction of the fluoroacetyl group into various chemical structures.
Research and Development
Used in biochemical research to study cellular respiration and enzyme inhibition, particularly the aconitase enzyme within the Krebs cycle. Its potent effects make it a valuable tool for understanding metabolic pathways.
Precursor for Specialty Chemicals
Can be used as a precursor for the synthesis of niche fluorinated compounds where the introduction of a two-carbon fluorinated unit is required. This includes some agrochemicals and materials science applications.
| Molecular weight | 78.04 |
|---|---|
| Empirical formula | C2H3FO2 |
Hazard statements
- H300Fatal if swallowed
- H314Causes severe skin burns and eye damage
- H400Very toxic to aquatic life
Precautionary statements
- P264Wash thoroughly after handling
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 2642 6.1 / PGI |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+,N |
| Risk statements (R) | 28-50 |
| Safety statements (S) | 20-22-26-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fluoroacetic acid used for?
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Fluoroacetic acid is primarily used as an intermediate in chemical synthesis and in biochemical research to study metabolic pathways and enzyme inhibition. Its extreme toxicity significantly limits its direct applications.
What are the CAS number and formula for Fluoroacetic acid?
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The CAS number for Fluoroacetic acid is 144-49-0, and its empirical formula is C2H3FO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fluoroacetic acid primarily for laboratory and research purposes. The exact grade and purity are detailed on the product specification sheet. TSS does not represent this product as USP, BP, or EP grade.
What are the primary safety concerns when handling Fluoroacetic acid?
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Fluoroacetic acid is extremely toxic (Danger, H300: Fatal if swallowed) and causes severe skin burns and eye damage (H314). It is also very toxic to aquatic life (H400). Strict safety protocols, including appropriate personal protective equipment (gloves, eye protection, respiratory protection) and working in a well-ventilated area or fume hood, are mandatory.
Is Fluoroacetic acid a controlled substance?
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Fluoroacetic acid is subject to strict regulations due to its high toxicity and potential for misuse. It is classified as a highly hazardous substance.
How is Fluoroacetic acid packed, shipped, and exported?
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Fluoroacetic acid is packed and shipped in accordance with stringent international regulations for hazardous materials, including UN 2642 classification. TSS ensures compliance for global export.
How can I request a sample or quote for Fluoroacetic acid?
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To request a sample or quote, please use the 'Request a Quote' or 'Contact Us' form on the Tech Serve Solutions website, providing your details and the product CAS number (144-49-0).
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