Podophyllotoxin
Podophyllotoxin (CAS: 518-28-5, C22H22O8) is a lignan with a molecular weight of 414.41 g/mol. This compound exhibits significant optical activity, with [α]20/D −110.7°. Primarily utilised in chemical synthesis and as a chiral building block, it is crucial for the development of complex molecules, particularly in asymmetric synthesis research. Supplied at 95% purity, it requires storage at 2-8°C.

Asymmetric Synthesis
Podophyllotoxin serves as a key chiral precursor in asymmetric synthesis, enabling the stereoselective construction of complex molecular architectures.
Chemical Synthesis
This compound is a valuable reagent in general chemical synthesis, facilitating the preparation of various organic compounds and intermediates.
Chiral Building Block
Its inherent chirality makes Podophyllotoxin an important building block for creating enantiomerically pure target molecules.
Complex Molecule Development
Researchers utilise Podophyllotoxin in the intricate process of developing and synthesising complex organic molecules for diverse applications.
| Molecular weight | 414.41 |
|---|---|
| Empirical formula | C22H22O8 |
| Assay | 95% |
| Optical activity | [α]20/D −110.7°, c = 1 in chloroform |
| Storage temperature | 2-8°C |
| Melting point | 183-184 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
- H310Fatal in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P302IF ON SKIN
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3462 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 21-25-36/37/38 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Podophyllotoxin used for?
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Podophyllotoxin is primarily used in asymmetric synthesis, chemical synthesis, as a chiral building block, and in the development of complex molecules.
What is the CAS number and chemical formula for Podophyllotoxin?
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The CAS number for Podophyllotoxin is 518-28-5, and its chemical formula is C22H22O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Podophyllotoxin at a purity of 95%. We do not represent this product as USP, BP, or EP grade.
How should Podophyllotoxin be handled and stored?
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Podophyllotoxin is a toxic substance (H301, H310) that causes skin irritation (H315) and serious eye irritation (H319). It may also cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges, must be used. Store at 2-8°C.
Is Podophyllotoxin a controlled substance?
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The provided data does not indicate that Podophyllotoxin is a controlled substance under international regulations commonly tracked in chemical catalogues.
How is Podophyllotoxin shipped by TSS?
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Podophyllotoxin is shipped as UN 3462, Class 6.1, Packing Group II, adhering to stringent transportation regulations for hazardous materials.
How can I request a sample or quote for Podophyllotoxin?
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To request a sample or obtain a quote for Podophyllotoxin, please contact the Tech Serve Solutions sales team through our official channels.
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