Pivalic anhydride
Pivalic anhydride (CAS: 1538-75-6), with the molecular formula [(CH3)3CCO]2O and a molecular weight of 186.25 g/mol, is a carboxylic acid anhydride. It serves as a versatile intermediate in organic synthesis, particularly in acylation reactions. This compound is valuable for introducing the pivaloyl group into various molecules across research and industrial applications. Tech Serve Solutions offers this chemical with a minimum purity of 98.0%.
- IUPAC
- 2,2-Dimethylpropionic anhydride
- Synonyms
- 2,2-Dimethylpropionic anhydride
![Pivalic anhydride ([(CH3)3CCO]2O) — chemical structure, CAS 1538-75-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1538-75-6.png&w=3840&q=75)
Organic Synthesis Intermediate
Pivalic anhydride is widely employed as a reagent in organic synthesis for the pivaloylation of alcohols, amines, and other nucleophiles. Its bulky tert-butyl group can impart specific steric and electronic properties to the resulting derivatives.
Pharmaceutical Precursor
It acts as a building block in the synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules. The pivaloyl moiety is often incorporated to modify the pharmacokinetic properties of drug candidates.
Agrochemical Development
This compound finds application in the research and development of novel agrochemicals, where it can be used to synthesise pesticides, herbicides, and other crop protection agents.
Material Science Research
Pivalic anhydride may be utilized in the development of specialised polymers and materials, leveraging its structure to modify material properties.
| Molecular weight | 186.25 |
|---|---|
| Linear formula | [(CH3)3CCO]2O |
| Assay | ≥98.0% (GC) |
| Boiling point | 193 °C(lit.) |
| Density | 0.918 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.409(lit.)n20/D 1.409 |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 57 °C / 134.6 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pivalic anhydride primarily used for?
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Pivalic anhydride is primarily used as a reagent in organic synthesis for introducing the pivaloyl group (tert-butylcarbonyl group) into molecules. It serves as a building block in the synthesis of pharmaceuticals, agrochemicals, and other complex organic compounds.
What is the CAS number and molecular formula for Pivalic anhydride?
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The CAS number for Pivalic anhydride is 1538-75-6, and its molecular formula is [(CH3)3CCO]2O.
What grade and purity does Tech Serve Solutions supply for Pivalic anhydride?
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Tech Serve Solutions supplies Pivalic anhydride with an assay of ≥98.0% (GC). We do not represent this product as USP, BP, or EP grade.
What are the main hazards associated with Pivalic anhydride?
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Pivalic anhydride is a flammable liquid and vapour (H226) and causes severe skin burns and eye damage (H314). It requires careful handling with appropriate personal protective equipment, including face shields, chemical-resistant gloves, and eye protection.
How is Pivalic anhydride shipped and exported by TSS?
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Pivalic anhydride is classified as UN 2920, Hazard Class 3(8), Packing Group II, indicating it is a flammable, corrosive liquid. TSS ensures compliant packaging and documentation for domestic and international shipments.
How can I request a sample or quote for Pivalic anhydride?
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To request a sample or a quote for Pivalic anhydride, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements and shipping details.
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