Piperonyloyl chloride
Piperonyloyl chloride (CAS: 25054-53-9, C8H5ClO3) is an organic acid chloride featuring the piperonyl group. With a molecular weight of 184.58 g/mol, it serves as a valuable reactive intermediate in organic synthesis. Its utility lies in its ability to introduce the piperonyl moiety into various molecules, making it a key building block for research and development in diverse chemical sectors.

Organic Synthesis Intermediate
Piperonyloyl chloride is employed as a reactive intermediate for the synthesis of more complex organic molecules. It is used to acylate amines, alcohols, and other nucleophiles, facilitating the construction of diverse chemical structures.
Pharmaceutical Research
This compound acts as a building block in the research and development of novel pharmaceutical agents. Its structure can be incorporated into potential drug candidates targeting various therapeutic areas.
Agrochemical Development
Piperonyloyl chloride finds application in the synthesis of compounds explored for agrochemical properties. It aids in developing new pesticides, herbicides, or other crop protection agents.
Fine Chemical Manufacturing
It is utilised in the broader fine chemical industry for the production of specialised organic compounds. Its reactivity allows for versatile transformations in multi-step synthesis processes.
| Molecular weight | 184.58 |
|---|---|
| Empirical formula | C8H5ClO3 |
| Assay | 99% |
| Boiling point | 155 °C/25 mmHg(lit.) |
| Melting point | 78-79 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 22-26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Piperonyloyl chloride used for?
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Piperonyloyl chloride is a reactive intermediate used in organic synthesis, particularly in pharmaceutical and agrochemical research, and fine chemical manufacturing.
What is the CAS number and chemical formula for Piperonyloyl chloride?
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The CAS number for Piperonyloyl chloride is 25054-53-9, and its chemical formula is C8H5ClO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Piperonyloyl chloride with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should Piperonyloyl chloride be handled?
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Piperonyloyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection. Ensure adequate ventilation.
Is Piperonyloyl chloride shipped internationally?
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Yes, Tech Serve Solutions exports Piperonyloyl chloride globally. It is classified under UN 3261, Class 8, Packing Group II for transport.
How can I request a sample or quote for Piperonyloyl chloride?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for Piperonyloyl chloride.
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