(2R)-(−)-Glycidyl 4-nitrobenzoate
(2R)-(−)-Glycidyl 4-nitrobenzoate (CAS: 106268-95-5) is a chiral epoxide with the molecular formula C10H9NO5 and a molecular weight of 223.18 g/mol. It serves as a valuable chiral building block in organic synthesis, particularly for asymmetric reactions. Its structure facilitates stereoselective transformations, making it a key intermediate in the synthesis of complex molecules and pharmaceutical research.
- IUPAC
- (R)-(−)-Glycidyl 4-nitrobenzoate,(R)-(−)-Oxirane-2-methanol 4-nitrobenzoate

Chiral Synthesis
Utilised as a chiral synthon for the stereoselective construction of complex organic molecules. The epoxide ring can be opened regio- and stereoselectively.
Pharmaceutical Intermediates
Serves as a key building block in the synthesis of various pharmaceutical agents where specific stereochemistry is crucial for biological activity.
Asymmetric Catalysis Research
Employed in the development of new asymmetric catalytic systems and methodologies, leveraging its defined stereochemistry.
Organic Building Block
A versatile reagent for introducing chiral epoxide functionality into organic scaffolds, enabling further derivatisation.
| Molecular weight | 223.18 |
|---|---|
| Empirical formula | C10H9NO5 |
| Assay | 98% |
| Optical activity | [α]19/D −37°, c = 1.08 in chloroform |
| Storage temperature | 2-8°C |
| Melting point | 60-62 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2R)-(−)-Glycidyl 4-nitrobenzoate used for?
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(2R)-(−)-Glycidyl 4-nitrobenzoate is primarily used as a chiral building block in asymmetric synthesis and for the preparation of pharmaceutical intermediates.
What is the CAS number and molecular formula for (2R)-(−)-Glycidyl 4-nitrobenzoate?
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The CAS number is 106268-95-5 and the molecular formula is C10H9NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2R)-(−)-Glycidyl 4-nitrobenzoate at a purity of 98%. We do not represent this product as USP, BP, or EP grade.
What are the primary safety concerns when handling (2R)-(−)-Glycidyl 4-nitrobenzoate?
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This compound is a Warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used.
How is (2R)-(−)-Glycidyl 4-nitrobenzoate shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, handling the packing and export of (2R)-(−)-Glycidyl 4-nitrobenzoate according to international shipping regulations.
How can I request a sample or quote for (2R)-(−)-Glycidyl 4-nitrobenzoate?
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Please contact our sales team via the website or direct email to request a sample or a quotation for (2R)-(−)-Glycidyl 4-nitrobenzoate.
What are the storage conditions for (2R)-(−)-Glycidyl 4-nitrobenzoate?
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It is recommended to store (2R)-(−)-Glycidyl 4-nitrobenzoate under refrigeration at 2-8°C.
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