(S)-1-Boc-3-cyanopyrrolidine
(S)-1-Boc-3-cyanopyrrolidine (CAS: 132945-78-9), a chiral heterocyclic building block with the formula C10H16N2O2 and a molecular weight of 196.25 g/mol, is a key intermediate in asymmetric synthesis. Its protected pyrrolidine structure and nitrile functionality make it valuable for the construction of complex molecules in chemical and pharmaceutical research and development.

Chiral Building Block in Organic Synthesis
Utilised as a stereochemically defined starting material for synthesising complex organic molecules, including pharmaceuticals and agrochemicals. Its pyrrolidine core and nitrile group offer versatile reaction sites for further functionalisation.
Intermediate for Pharmaceutical Research
Serves as a crucial intermediate in the development of novel drug candidates. The chiral nature of this compound is essential for creating enantiomerically pure active pharmaceutical ingredients (APIs).
Asymmetric Synthesis Applications
Key component in asymmetric synthesis, enabling the controlled formation of chiral centres. Its application is vital for researchers aiming to produce specific stereoisomers of target compounds.
| Molecular weight | 196.25 |
|---|---|
| Empirical formula | C10H16N2O2 |
| Assay | ≥95.5% (HPLC)96% |
| Optical activity | [α]/D +24.0±2.0°, c = 1 in methanol |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-Boc-3-cyanopyrrolidine used for?
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(S)-1-Boc-3-cyanopyrrolidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in pharmaceutical research and chemical synthesis. It aids in the construction of complex, stereochemically defined molecules.
What are the CAS number and formula for (S)-1-Boc-3-cyanopyrrolidine?
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The CAS number for (S)-1-Boc-3-cyanopyrrolidine is 132945-78-9, and its empirical formula is C10H16N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-1-Boc-3-cyanopyrrolidine with an assay of ≥95.5% (HPLC) or 96%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should (S)-1-Boc-3-cyanopyrrolidine be handled?
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According to GHS, (S)-1-Boc-3-cyanopyrrolidine is a Warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle in a well-ventilated area, avoiding contact with skin, eyes, and clothing. Wear appropriate personal protective equipment.
Is (S)-1-Boc-3-cyanopyrrolidine a controlled substance?
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The provided data does not indicate that (S)-1-Boc-3-cyanopyrrolidine is a controlled substance.
How is (S)-1-Boc-3-cyanopyrrolidine packed and shipped?
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As a specialist global supplier, Tech Serve Solutions ensures that (S)-1-Boc-3-cyanopyrrolidine is appropriately packed for safe transit and export according to international regulations.
How can I request a sample or quote for (S)-1-Boc-3-cyanopyrrolidine?
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To request a sample or a quote for (S)-1-Boc-3-cyanopyrrolidine, please use the contact form on our website or contact our sales team directly.
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