3-(Trifluoromethyl)benzoic acid
3-(Trifluoromethyl)benzoic acid (CAS 454-92-2), with the molecular formula CF3C6H4CO2H and a molecular weight of 190.12 g/mol, is a valuable organic building block. This trifluoromethylated aromatic carboxylic acid serves as a key intermediate in various chemical syntheses, particularly within the pharmaceutical and agrochemical industries. Its structure allows for diverse functionalisation, making it a versatile reagent for creating complex molecules.
- IUPAC
- α,α,α-Trifluoro-m-toluic acid,3-Carboxybenzotrifluoride
- Synonyms
- α,α,α-Trifluoro-m-toluic acid3-Carboxybenzotrifluoride
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs). The trifluoromethyl group can enhance lipophilicity and metabolic stability of drug candidates.
Agrochemical Synthesis
Serves as a building block for the development of novel pesticides and herbicides. Its structural features can contribute to the efficacy and persistence of agricultural chemicals.
Organic Synthesis Reagent
A versatile reagent for introducing the 3-(trifluoromethyl)benzoyl moiety into organic molecules. It is employed in research and development for creating new chemical entities.
Material Science
Investigated for its potential incorporation into advanced materials, leveraging the unique electronic properties conferred by the trifluoromethyl substituent.
| Molecular weight | 190.12 |
|---|---|
| Linear formula | CF3C6H4CO2H |
| Assay | ≥98.0% (T) |
| Boiling point | 238.5 °C/775 mmHg(lit.) |
| Melting point | 101-106 °C104-106 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trifluoromethyl)benzoic acid used for?
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3-(Trifluoromethyl)benzoic acid is primarily used as a building block in organic synthesis, particularly for the preparation of pharmaceuticals and agrochemicals. It also finds applications in material science and general chemical research.
What are the CAS number and chemical formula for 3-(Trifluoromethyl)benzoic acid?
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The CAS number is 454-92-2 and the chemical formula is CF3C6H4CO2H.
What grade and purity does Tech Serve Solutions supply for 3-(Trifluoromethyl)benzoic acid?
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Tech Serve Solutions supplies 3-(Trifluoromethyl)benzoic acid with an assay of ≥98.0% (T). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-(Trifluoromethyl)benzoic acid be handled safely?
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Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust/fume/gas/mist/vapours/spray. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical advice. Store in a well-ventilated place.
Is 3-(Trifluoromethyl)benzoic acid suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-(Trifluoromethyl)benzoic acid.
How can I request a sample or quote for 3-(Trifluoromethyl)benzoic acid?
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Please contact our sales team via the website or by phone to request a sample or a detailed quote for 3-(Trifluoromethyl)benzoic acid.
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