3-(Trifluoromethyl)benzyl bromide

CAS 402-23-3CF3C6H4CH2BrChemical Synthesis

3-(Trifluoromethyl)benzyl bromide (CAS 402-23-3) is an organobromine compound with the molecular formula CF3C6H4CH2Br and a molecular weight of 239.03 g/mol. This aryl building block serves as a crucial intermediate in organic synthesis. It is notably used in the preparation of Flocoumafen, a rodenticide. Available at a purity of 98%, it is suitable for various chemical synthesis applications.

IUPAC: α′-Bromo-α,α,α-trifluoro-m-xylene

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3-(Trifluoromethyl)benzyl bromide (CF3C6H4CH2Br) — chemical structure, CAS 402-23-3; Chemistry, fine chemical supplied by Tech Serve Solutions

ArylBuilding BlocksChemical SynthesisHalogenated Hydrocarbons

01 /Applications

Intermediate in Flocoumafen Synthesis

3-(Trifluoromethyl)benzyl bromide is a key precursor in the multi-step synthesis of Flocoumafen, a widely used anticoagulant rodenticide. Its benzyl bromide functionality allows for facile alkylation reactions in constructing the complex Flocoumafen molecule.

Organic Building Block

As a trifluoromethyl-substituted benzyl bromide, this compound is a valuable building block in organic chemistry. The trifluoromethyl group imparts unique electronic and lipophilic properties, making it useful for introducing this moiety into diverse molecular structures.

Chemical Synthesis

This reagent is employed in various chemical synthesis pathways where a reactive benzylic bromide bearing a trifluoromethyl group is required. It facilitates the formation of new carbon-carbon or carbon-heteroatom bonds.

02 /Properties

Molecular weight	239.03
Linear formula	CF3C6H4CH2Br
Assay	98%
Boiling point	69 °C/4 mmHg(lit.)
Density	1.565 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.492(lit.)
Application	3-(Trifluoromethyl)benzyl bromide has been used in the preparation of flocoumafen1.

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	88 °C / 190.4 °F
Transport (UN / ADR)	UN 3265 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

402-23-3

MDL number

MFCD00000395

PubChem substance

24857473

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-(Trifluoromethyl)benzyl bromide used for?

3-(Trifluoromethyl)benzyl bromide (CAS 402-23-3) is primarily used as an intermediate in the synthesis of Flocoumafen and as a general building block in organic chemical synthesis.

What are the CAS number and formula for 3-(Trifluoromethyl)benzyl bromide?

The CAS number is 402-23-3, and the molecular formula is CF3C6H4CH2Br.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 3-(Trifluoromethyl)benzyl bromide with a purity of 98%. This is a technical/research grade material; TSS does not represent it as USP, BP, or EP grade.

How should 3-(Trifluoromethyl)benzyl bromide be handled safely?

3-(Trifluoromethyl)benzyl bromide is classified as Danger (GHS05) due to its corrosive properties (H314). Handle with extreme care, using appropriate personal protective equipment including gloves, goggles, a faces shield, and suitable respiratory protection. Refer to the Safety Data Sheet for full handling instructions.

How is 3-(Trifluoromethyl)benzyl bromide packed and shipped?

This chemical is packed and shipped in compliance with international regulations for hazardous materials, identified as UN 3265, Class 8, Packing Group II. We are experienced global exporters.

How can I request a quote or sample for 3-(Trifluoromethyl)benzyl bromide?

To request a quote or sample, please contact our sales department via the 'Contact Us' form on our website or by calling our direct line. Please specify the quantity required and your shipping destination.