1-(3,4-Dichlorophenyl)piperazine
1-(3,4-Dichlorophenyl)piperazine (CAS 57260-67-0) is a halogenated aryl-piperazine building block with the molecular formula C10H12Cl2N2 and a molar mass of 231.12 g/mol. Supplied as a solid (melting point 62-66 °C) at an assay of ≥98.0% (GC), it serves chiefly as an intermediate in organic and medicinal chemistry, where its secondary piperazine nitrogen and 3,4-dichlorophenyl ring support N-functionalisation, alkylation and acylation in research-scale synthesis.
- Synonyms
- 1-(3,4-Dichlorophenyl)piperazine3,4-Dichlorophenylpiperazine1-(3,4-Dichlorophenyl)piperazine free base3,4-DCPPCAS 57260-67-0C10H12Cl2N2
Pharmaceutical and medicinal-chemistry intermediate
Used as an aryl-piperazine building block in the synthesis of more elaborate molecules. The reactive secondary amine allows alkylation, acylation and reductive amination to install diverse side chains.
Heterocyclic building block for chemical synthesis
Acts as a versatile C10 halogenated heterocyclic scaffold. The piperazine ring and dichloroaryl group provide convenient handles for constructing piperazine-derived targets.
Discovery and structure-activity research
Employed in research laboratories to prepare analogue libraries around the aryl-piperazine motif, supporting exploration of structure-activity relationships.
Reference and analytical use
Its defined identity (CAS 57260-67-0, MDL MFCD00023128) and ≥98.0% GC purity make it suitable as a characterised reagent for method development and comparative work.
| Molecular weight | 231.12 |
|---|---|
| Empirical formula | C10H12Cl2N2 |
| Assay | ≥98.0% (GC) |
| Melting point | 62-66 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3,4-Dichlorophenyl)piperazine used for?
+
It is used primarily as a building block and intermediate in organic and medicinal chemistry. The free secondary nitrogen on the piperazine ring undergoes alkylation, acylation and reductive amination, making it useful for assembling more complex aryl-piperazine compounds in research-scale synthesis.
What is the CAS number and molecular formula of 1-(3,4-Dichlorophenyl)piperazine?
+
The CAS number is 57260-67-0 and the molecular formula is C10H12Cl2N2. The molecular weight is 231.12 g/mol, the EC number is 260-652-9 and the MDL number is MFCD00023128. It is a solid with a melting point of 62-66 °C.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1-(3,4-Dichlorophenyl)piperazine at an assay of ≥98.0% (GC) as a research/technical-grade material. We do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements for 1-(3,4-Dichlorophenyl)piperazine?
+
It carries GHS07 with the signal word Warning and the hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and an N95-type dust mask, avoid dust formation, and follow the precautionary advice P261 and P305+P351+P338. It is rated WGK 3 (highly hazardous to water), so prevent release to drains and the environment. Always consult the SDS before use.
How is 1-(3,4-Dichlorophenyl)piperazine packed, shipped and exported?
+
It is packed as a solid in tightly closed, labelled containers sized to the order, from research quantities to bulk, with secondary protection for transit. As a specialist exporter, Tech Serve Solutions ships internationally with full documentation, including the SDS and certificate of analysis, in line with applicable transport and customs requirements.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with your required quantity, purity and destination, and we will respond with availability, lead time and documentation. Samples may be available subject to stock and applicable regulatory checks.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis