1-(3,4-Dihydro-2-naphthyl)pyrrolidine
1-(3,4-Dihydro-2-naphthyl)pyrrolidine (CAS 21403-95-2; C14H17N; molar mass 199.29 g/mol) is the pyrrolidine enamine derived from 2-tetralone, supplied as a crystalline solid melting at about 82-84 C. As a nucleophilic enamine building block it is used in organic and medicinal chemistry synthesis to functionalise the tetralone framework. Tech Serve Solutions supplies this heterocyclic intermediate at 97% assay for research and manufacturing use worldwide.
- Synonyms
- 1-(3,4-Dihydro-2-naphthyl)pyrrolidine1-(3,4-Dihydronaphthalen-2-yl)pyrrolidine2-(1-Pyrrolidinyl)-3,4-dihydronaphthalene3,4-Dihydro-2-(1-pyrrolidinyl)naphthalenePyrrolidine enamine of 2-tetralone2-tetralone pyrrolidine enamine
Enamine building block
The compound is the pyrrolidine enamine of 2-tetralone and serves as a nucleophilic synthon for carbon-carbon bond formation. It is used in classical enamine (Stork-type) chemistry to functionalise the position alpha to the original ketone.
Tetralin and naphthalenone synthesis
It provides convenient access to substituted 3,4-dihydronaphthalen-2(1H)-one (2-tetralone) derivatives after alkylation or acylation and hydrolysis. This makes it a useful intermediate for elaborating the partially saturated naphthalene scaffold.
Pharmaceutical and fine-chemical intermediate
As a heterocyclic building block in the C13-C20+ range, it is employed in medicinal-chemistry and fine-chemical research programmes. It is offered for synthetic use and is not represented as a finished active pharmaceutical ingredient.
Research and laboratory reagent
Supplied at 97% assay, it is suited to discovery chemistry, methodology studies and small-scale process development. Cold storage at 2-8 C helps preserve the reactive enamine during handling and storage.
| Molecular weight | 199.29 |
|---|---|
| Empirical formula | C14H17N |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 82-84 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3,4-Dihydro-2-naphthyl)pyrrolidine used for?
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It is used primarily as an enamine building block in chemical synthesis. Being the pyrrolidine enamine of 2-tetralone, it acts as a nucleophilic intermediate for carbon-carbon bond formation and for preparing substituted tetralone and dihydronaphthalene derivatives in research and fine-chemical manufacture.
What is the CAS number and molecular formula of 1-(3,4-Dihydro-2-naphthyl)pyrrolidine?
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Its CAS number is 21403-95-2 and its molecular formula is C14H17N, with a molecular weight of 199.29 g/mol. The EC number is 244-371-9 and the MDL number is MFCD00001674.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this material at a typical assay of 97% as a research and synthesis-grade chemical. It is not represented as USP, BP or EP pharmacopoeia grade; a certificate of analysis is provided with each batch.
What are the safety and handling requirements?
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It is classified under GHS07 with the signal word Warning and hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Wear gloves, eye protection and an N95-type dust mask, avoid dust formation, and follow precautionary advice P261 and P305+P351+P338. It carries German water-hazard class WGK 3, so prevent release to the environment.
How should 1-(3,4-Dihydro-2-naphthyl)pyrrolidine be stored?
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Store refrigerated at 2-8 C in a tightly closed container, protected from moisture and air, as enamines are moisture-sensitive. The compound is a solid melting at about 82-84 C.
How is 1-(3,4-Dihydro-2-naphthyl)pyrrolidine packed, shipped and exported?
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It is packed in suitable sealed containers with sizes from gram to kilogram quantities, fully labelled and accompanied by a certificate of analysis and safety data sheet. Tech Serve Solutions exports worldwide under applicable transport and customs regulations, with packaging selected to maintain the recommended cold-chain storage.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name, CAS number 21403-95-2 and your required quantity to receive a quotation or arrange a sample. Our team can confirm current availability, specifications and lead times for your destination.
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