1-(3,5-Dichlorophenyl)biguanide hydrochloride
1-(3,5-Dichlorophenyl)biguanide hydrochloride (CAS 175205-04-6) is an aryl-substituted biguanide salt with the linear formula Cl₂C₆H₃NHCNHNHCNHNH₂ · HCl and a molecular weight of 282.56. Supplied as a crystalline solid (melting point 251–255 °C), it serves principally as an organic building block and synthetic intermediate. The biguanide moiety makes it a useful precursor for constructing nitrogen heterocycles such as triazines and pyrimidines in research and fine-chemical synthesis.
- Synonyms
- 1-(3,5-Dichlorophenyl)biguanide hydrochlorideN-(3,5-dichlorophenyl)imidodicarbonimidic diamide hydrochloride3,5-dichlorophenylbiguanide hydrochlorideCl₂C₆H₃NHCNHNHCNHNH₂ · HClMFCD00173888CAS 175205-04-6

Organic building block
Used as a multifunctional building block in chemical synthesis, providing a dichlorophenyl-substituted biguanide scaffold for further elaboration.
Heterocycle synthesis
The biguanide group is a classical precursor to nitrogen heterocycles, allowing cyclisation toward 1,3,5-triazines, dihydrotriazines and related pyrimidine systems.
Pharmaceutical and agrochemical intermediate
Serves as an intermediate in exploratory medicinal-chemistry and agrochemical programmes where a guanidine or biguanide functionality is required on an aromatic core.
Laboratory reagent
Employed as a reagent and reference material in research laboratories for method development and small-scale synthetic studies.
| Molecular weight | 282.56 |
|---|---|
| Linear formula | Cl2C6H3NHCNHNHCNHNH2 · HCl |
| Assay | 97% |
| Melting point | 251-255 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3,5-Dichlorophenyl)biguanide hydrochloride used for?
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It is used mainly as an organic building block and synthetic intermediate. The biguanide functionality makes it a precursor for nitrogen heterocycles such as triazines and pyrimidines, and it is applied in research-scale pharmaceutical and agrochemical synthesis.
What is the CAS number and molecular formula of 1-(3,5-Dichlorophenyl)biguanide hydrochloride?
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The CAS number is 175205-04-6. The linear formula is Cl₂C₆H₃NHCNHNHCNHNH₂ · HCl (corresponding to C₈H₉Cl₂N₅ · HCl), with a molecular weight of 282.56. Its MDL number is MFCD00173888.
What grade and purity does Tech Serve Solutions supply?
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We supply this material at a typical assay of 97% as a research and technical-grade product. We do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements for this compound?
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It is classified under GHS07 with the signal word Warning and hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and an N95-type dust mask, and avoid generating dust. It is rated WGK 3, indicating it is severely hazardous to water; consult the SDS before use.
How is 1-(3,5-Dichlorophenyl)biguanide hydrochloride packed, shipped and exported?
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It is packed as a solid in tightly sealed containers sized to the order, from gram quantities to bulk, with full labelling and documentation. Tech Serve Solutions exports worldwide with the required compliance and transport paperwork for each destination.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and we will provide a quotation, available documentation and lead time. Samples can be arranged subject to availability.
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