1-(3,5-Dimethylphenyl)piperazin-2-one
1-(3,5-Dimethylphenyl)piperazin-2-one (CAS 880361-76-2) is a substituted piperazin-2-one building block with the molecular formula C12H16N2O and a molar mass of 204.27 g/mol. The molecule combines a six-membered piperazinone (lactam) ring with a 3,5-dimethylphenyl group on the nitrogen, giving a versatile, nitrogen-rich heterocyclic scaffold. Tech Serve Solutions supplies it as a research-grade fine chemical for laboratory and synthetic chemistry, where it serves chiefly as an intermediate in pharmaceutical and chemical synthesis.
- Synonyms
- 1-(3,5-Dimethylphenyl)piperazin-2-one1-(3,5-Dimethylphenyl)-2-piperazinone1-(3,5-dimethylphenyl)-piperazin-2-oneC12H16N2OCAS 880361-76-2

Pharmaceutical synthesis intermediate
Used as a heterocyclic building block in medicinal chemistry and active pharmaceutical ingredient (API) route development. The piperazin-2-one ring is a common motif in drug-discovery scaffolds, making this compound a useful intermediate for synthetic programmes.
Heterocyclic building block
Serves as a defined piperazinone scaffold for assembling more complex nitrogen-containing molecules. The lactam carbonyl and ring nitrogen offer convenient handles for further functionalisation and derivatisation.
Chemical synthesis and research
Applied in general organic and process-chemistry research where a 3,5-dimethylphenyl-substituted piperazin-2-one is required. Suitable for exploratory route-scouting and structure-activity studies at laboratory scale.
Reference and laboratory reagent
Employed by research and quality-control laboratories as a characterised reagent for method development and comparative work. Supplied with documentation to support identity and traceability.
| Molecular weight | 204.27 |
|---|---|
| Empirical formula | C12H16N2O |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3,5-Dimethylphenyl)piperazin-2-one used for?
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It is used mainly as a heterocyclic building block and synthetic intermediate in pharmaceutical and chemical research. The piperazin-2-one (piperazinone) ring is a frequent scaffold in medicinal chemistry, so the compound supports route development, derivatisation and laboratory-scale synthesis.
What is the CAS number and molecular formula of 1-(3,5-Dimethylphenyl)piperazin-2-one?
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The CAS number is 880361-76-2. The molecular formula is C12H16N2O (Hill notation) with a molecular weight of 204.27 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply 1-(3,5-Dimethylphenyl)piperazin-2-one as a research- and technical-grade fine chemical for laboratory and synthesis use. We do not represent it as USP, BP or EP pharmacopoeial grade. The exact assay and specification for a given lot are confirmed on the certificate of analysis, which is available on request.
How should 1-(3,5-Dimethylphenyl)piperazin-2-one be handled and stored?
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Handle it as a research chemical using standard laboratory good practice: wear suitable gloves, eye protection and a lab coat, avoid dust formation, and work with adequate ventilation. Store in a tightly closed container in a cool, dry, well-ventilated place away from incompatible materials. A full Safety Data Sheet with the current GHS classification accompanies every shipment and should be reviewed before use.
How is 1-(3,5-Dimethylphenyl)piperazin-2-one packed, shipped and exported?
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It is packed in appropriately sealed, labelled laboratory containers sized to the order, from gram to bulk quantities, with tamper-evident closures. Each consignment ships with a certificate of analysis and Safety Data Sheet, and as a global supplier and exporter since 1998 we arrange compliant international documentation and freight to suit your destination.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS number 880361-76-2, the quantity required and your delivery location. We will confirm availability, lead time, specification and packing options, and provide a quotation; samples can be discussed for qualified laboratory and commercial enquiries.
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