2-(Dimethylamino)pyrimidine-5-boronic acid pinacol ester
2-(Dimethylamino)pyrimidine-5-boronic acid pinacol ester (CAS: 1032759-30-0; Formula: C12H20BN3O2; MW: 249.12) is a valuable organoboronate ester. This compound serves as a crucial building block in organic synthesis, particularly for cross-coupling reactions. It is frequently employed in the development of novel pharmaceutical agents and advanced materials due to its versatile reactivity. Tech Serve Solutions supplies this reagent with a minimum assay of 97%.
- IUPAC
- 2-(Dimethylamino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
- Synonyms
- 2-(Dimethylamino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
Suzuki-Miyaura Coupling Reagent
This pinacol ester is a key substrate in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds with aryl and vinyl halides. It is instrumental in constructing complex organic molecules.
Pharmaceutical Intermediate Synthesis
The compound is utilised as a synthon in the preparation of active pharmaceutical ingredients (APIs). Its pyrimidine core and boronic ester functionality are valuable for introducing specific structural motifs.
Materials Science Research
It can be incorporated into the synthesis of functional organic materials, such as those used in organic electronics or optoelectronic devices, owing to its heterocyclic and boron functionalities.
| Molecular weight | 249.12 |
|---|---|
| Empirical formula | C12H20BN3O2 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 107-112 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Dimethylamino)pyrimidine-5-boronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and in the development of pharmaceutical intermediates and novel materials.
What are the CAS number and formula for this product?
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The CAS number is 1032759-30-0 and the empirical formula (Hill notation) is C12H20BN3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a minimum assay of 97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
How should this chemical be handled safely?
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This compound may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. Store at 2-8°C.
Is this chemical available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-(Dimethylamino)pyrimidine-5-boronic acid pinacol ester.
How can I request a sample or quote?
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To request a sample or a quotation, please contact our sales team through the website or by phone, providing the product name and CAS number.
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