2-(Dimethylamino)pyridine
2-(Dimethylamino)pyridine (CAS 5683-33-0, C7H10N2, MW 122.17) is a versatile organic compound and a substituted pyridine derivative. It functions as a useful building block in chemical synthesis, particularly within the realm of heterocyclic chemistry. Its properties make it suitable for various organic transformations, enabling the construction of more complex molecular architectures.
Synthesis of Pyridinium Salts
Reacts with alkylating agents like methyl trifluoromethanesulfonate to form pyridinium salts. For example, in toluene at room temperature, it yields (2-pyridyl)-trimethylammonium trifluoromethanesulfonate salt.
Heterocyclic Building Block
Serves as a key intermediate in the synthesis of various heterocyclic compounds. Its pyridine core and dimethylamino substituent offer reactive sites for further functionalization.
Organic Synthesis Reagent
Employed in diverse organic transformations due to its nucleophilic and basic properties inherent to the pyridine ring and the amino group.
| Molecular weight | 122.17 |
|---|---|
| Empirical formula | C7H10N2 |
| Assay | 97% |
| Boiling point | 191 °C(lit.) |
| Density | 0.984 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.559(lit.) |
| Application | 2-(Dimethylamino)pyridine in toluene at room temperature in the presence of 1.1 equivalent of methyl trifluoromethanesulfonate forms (2-pyridyl)-trimethylammonium trifluoromethanesulfonate salt 1. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 23-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Dimethylamino)pyridine used for?
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2-(Dimethylamino)pyridine is used as a building block in chemical synthesis and for the preparation of pyridinium salts.
What are the CAS number and formula for 2-(Dimethylamino)pyridine?
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The CAS number is 5683-33-0 and the empirical formula is C7H10N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Dimethylamino)pyridine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-(Dimethylamino)pyridine be handled safely?
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2-(Dimethylamino)pyridine is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation.
How is 2-(Dimethylamino)pyridine packed and shipped?
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2-(Dimethylamino)pyridine is shipped according to relevant transportation regulations, such as NA 1993 / PGIII for ground transport. We handle export documentation and logistics.
How can I request a quote or sample of 2-(Dimethylamino)pyridine?
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Please contact the TSS sales team via our website or direct inquiry to request a quote or a sample of 2-(Dimethylamino)pyridine.
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