2-(Dimethylsilyl)pyridine
2-(Dimethylsilyl)pyridine (CAS 21032-48-4) is an organosilicon compound with the linear formula (C5H4N)Si(CH3)2H and a molecular weight of 137.25 g/mol. This heterocyclic building block serves as a valuable scaffold in chemical synthesis. Its reactivity profile makes it useful for various transformations, including hydrosilylation and cross-coupling reactions, contributing to the development of novel organic molecules and materials.
- IUPAC
- Dimethyl(2-pyridyl)silane
- Synonyms
- Dimethyl(2-pyridyl)silane

Hydrosilylation Reactions
2-(Dimethylsilyl)pyridine is employed in hydrosilylation processes, where a silicon-hydrogen bond adds across an unsaturated bond. This reaction is fundamental in the synthesis of organosilicon compounds.
Cross-Coupling Chemistry
This compound can participate in cross-coupling reactions, offering a route to create new carbon-carbon or carbon-heteroatom bonds. It is a versatile building block for complex molecule construction.
Olefination Processes
Utilised in olefination reactions, 2-(Dimethylsilyl)pyridine contributes to the formation of carbon-carbon double bonds, a key transformation in organic synthesis.
Organosilicon Synthesis
As an organosilicon reagent, it is instrumental in the synthesis of diverse organosilicon compounds, finding applications in materials science and specialised chemical manufacturing.
| Molecular weight | 137.25 |
|---|---|
| Linear formula | (C5H4N)Si(CH3)2H |
| Assay | 90% |
| Density | 0.915 g/mL at 25 °C |
| Refractive index | n20/D 1.499 |
| Storage temperature | 2-8°C |
| Application | A useful scaffold for a number of reactions including hydrosilylation, cross-coupling, and olefination.1 |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 40 °C / 104 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Dimethylsilyl)pyridine used for?
+
2-(Dimethylsilyl)pyridine is a valuable scaffold for reactions including hydrosilylation, cross-coupling, and olefination, making it useful in organic synthesis and organosilicon chemistry.
What are the CAS number and chemical formula for 2-(Dimethylsilyl)pyridine?
+
The CAS number is 21032-48-4 and the linear chemical formula is (C5H4N)Si(CH3)2H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-(Dimethylsilyl)pyridine with a minimum assay of 90%. We do not represent this product as USP, BP, EP, or for pharmaceutical, food, or nutraceutical use.
How should 2-(Dimethylsilyl)pyridine be handled safely?
+
2-(Dimethylsilyl)pyridine is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area. Store at 2-8°C.
Is 2-(Dimethylsilyl)pyridine available for export?
+
Yes, Tech Serve Solutions specialises in global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample for 2-(Dimethylsilyl)pyridine?
+
Please contact our sales team via our website or provide your details through the product page to request a quote or sample.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis