2,3,4-Trifluorobenzenesulfonyl chloride
2,3,4-Trifluorobenzenesulfonyl chloride (CAS: 175278-08-7) is a fluorinated organic building block with the linear formula F 3C6H2SO2Cl and a molecular weight of 230.59 g/mol. This sulfonyl halide is a key intermediate in organic synthesis. Its unique trifluorinated phenyl ring makes it valuable for introducing specific structural motifs in the development of novel pharmaceuticals, agrochemicals, and advanced materials. It is supplied by TSS with a purity of 97%.
- Synonyms
- 175278-08-7F3C6H2SO2Cl

Pharmaceutical Synthesis
Utilised as a building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), leveraging its fluorinated structure for enhanced drug properties.
Agrochemical Development
Incorporated into the design and synthesis of new pesticides, herbicides, and fungicides, where fluorine substitution can improve efficacy and metabolic stability.
Materials Science
Employed in the creation of advanced polymers and specialty materials, where the trifluorobenzenesulfonyl moiety can impart unique thermal or electronic characteristics.
Organic Synthesis Intermediate
Serves as a versatile reagent for introducing the 2,3,4-trifluorobenzenesulfonyl group into various organic molecules via sulfonylation reactions.
| Molecular weight | 230.59 |
|---|---|
| Linear formula | F3C6H2SO2Cl |
| Assay | 97% |
| Boiling point | 234-236 °C(lit.) |
| Density | 1.640 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5040(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4-Trifluorobenzenesulfonyl chloride used for?
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2,3,4-Trifluorobenzenesulfonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and chemical formula for 2,3,4-Trifluorobenzenesulfonyl chloride?
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The CAS number is 175278-08-7, and the linear formula is F3C6H2SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3,4-Trifluorobenzenesulfonyl chloride with an assay of 97%. This product is not represented as USP/BP/EP grade.
How should 2,3,4-Trifluorobenzenesulfonyl chloride be handled safely?
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This compound causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, goggles, face shields, and respiratory protection. Ensure good ventilation and avoid contact with skin, eyes, and clothing. Refer to the Safety Data Sheet (SDS) for detailed handling procedures.
Is 2,3,4-Trifluorobenzenesulfonyl chloride suitable for export?
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Yes, Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, including 2,3,4-Trifluorobenzenesulfonyl chloride, adhering to all necessary shipping and regulatory requirements.
How can I request a quote or sample?
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To request a quote or a sample of 2,3,4-Trifluorobenzenesulfonyl chloride, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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