2-Benzylimidazoline
2-Benzylimidazoline (CAS: 59-98-3) is a heterocyclic organic compound with the formula C10H12N2 and a molecular weight of 160.22 g/mol. It serves as a valuable building block in chemical synthesis, particularly for creating complex heterocyclic structures. Its known applications include its use in the preparation of phenyl-2,3-dihydroimidazo[1,2-a]pyridinone derivatives, making it a useful reagent in medicinal chemistry and materials science research.
- IUPAC
- 2-Benzyl-2-imidazoline,2-Benzyl-4,5-dihydro-1H-imidazole,Benzidazol,NSC 35110,Phenylmethylimidazoline,Tolazoline
Synthesis of Dihydroimidazo[1,2-a]pyridinone Derivatives
2-Benzylimidazoline has been utilised in condensation reactions with β-keto esters to synthesise phenyl-2,3-dihydroimidazo[1,2-a]pyridinone derivatives. This application highlights its utility in constructing fused heterocyclic systems of potential pharmaceutical interest.
Chemical Synthesis Building Block
As a heterocyclic building block, 2-Benzylimidazoline is employed in organic synthesis for the construction of more complex molecules. Its structure offers reactive sites suitable for various chemical transformations and derivatizations.
Research in Bioactive Small Molecules
This compound falls within the category of bioactive small molecules and heterocyclic building blocks, indicating its potential use in drug discovery research and the development of new biologically active compounds.
| Molecular weight | 160.22 |
|---|---|
| Empirical formula | C10H12N2 |
| Assay | 99% |
| Solubility | alcohol: freely solublechloroform: solublediethyl ether: very slightly solubleethyl acetate: very slightly solublewater: freely soluble |
| Storage temperature | 2-8°C |
| Application | 2-Benzylimidazoline has been used in the preparation of phenyl-2,3-dihydroimidazo[1,2-a]pyridinone derivatives via condensation with of a series of β-keto esters1. |
| Melting point | 66-69 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HTR1B(3351), HTR1D(3352) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Benzylimidazoline used for?
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2-Benzylimidazoline is used in chemical synthesis, particularly for preparing phenyl-2,3-dihydroimidazo[1,2-a]pyridinone derivatives and as a general heterocyclic building block in organic synthesis and medicinal chemistry research.
What are the CAS number and chemical formula for 2-Benzylimidazoline?
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The CAS number for 2-Benzylimidazoline is 59-98-3, and its chemical formula is C10H12N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Benzylimidazoline with an assay of 99%. This product is intended for research and laboratory use. Tech Serve Solutions does not represent this product as USP, BP, EP or any other pharmacopoeia grade.
How should 2-Benzylimidazoline be handled safely?
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2-Benzylimidazoline is a warning substance. It is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, face shields, and gloves. Ensure adequate ventilation.
How is 2-Benzylimidazoline packed and shipped?
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2-Benzylimidazoline is typically stored at 2-8°C. It is supplied by Tech Serve Solutions, a global supplier and exporter, and is packaged according to industry standards for safe transport.
How can I request a sample or quote for 2-Benzylimidazoline?
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To request a sample or a quote for 2-Benzylimidazoline, please contact the Tech Serve Solutions sales team through the website or by phone.
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