2-Benzyloxy-1-methylpyridinium triflate
2-Benzyloxy-1-methylpyridinium triflate (CAS: 882980-43-0) is a chemical compound with the formula C14H14F3NO4S and a molecular weight of 349.33 g/mol. This reagent serves as a valuable tool in organic synthesis, particularly for the selective benzylation of alcohols and carboxylic acids under neutral conditions. Its specific reactivity makes it useful for protecting functional groups in complex molecular architectures, facilitating advanced synthetic strategies.
- IUPAC
- Bn-OPT,Dudley Reagent
Benzyl Protection of Alcohols
This compound acts as a novel reagent for the neutral benzyl protection of alcohols. It enables selective formation of benzyl ethers, a common protecting group strategy in multi-step synthesis.
Selective Benzyl Ester Formation
It promotes the selective formation of benzyl esters from carboxylic acids, even in the presence of other functional groups like tertiary amines. This offers a controlled method for esterification.
Dudley Reagents
2-Benzyloxy-1-methylpyridinium triflate belongs to the class of Dudley Reagents, which are recognized for their specific applications in modern chemical synthesis and functional group manipulation.
| Molecular weight | 349.33 |
|---|---|
| Empirical formula | C14H14F3NO4S |
| Assay | 96% |
| Storage temperature | 2-8°C |
| Application | Dudley Reagents• Novel reagent for benzyl protection of alcohols under neutral conditions.1,2 Promotes selective formation of benzyl esters of carboxylic acids in presence of triethylamine.3 |
| Melting point | 85-91 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Benzyloxy-1-methylpyridinium triflate used for?
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2-Benzyloxy-1-methylpyridinium triflate is primarily used as a reagent for the selective benzylation of alcohols and the formation of benzyl esters of carboxylic acids under neutral conditions.
What are the CAS number and formula for 2-Benzyloxy-1-methylpyridinium triflate?
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The CAS number is 882980-43-0 and the empirical formula is C14H14F3NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Benzyloxy-1-methylpyridinium triflate at a purity of 96%. This product is supplied for research and development purposes and is not intended for use as a USP, BP, EP, or pharmaceutical-grade substance.
How should 2-Benzyloxy-1-methylpyridinium triflate be handled safely?
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Handle 2-Benzyloxy-1-methylpyridinium triflate with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation, as it can cause respiratory irritation (H335). Avoid contact with eyes, skin, and clothing as it is corrosive and an irritant (H315, H318). It is harmful if swallowed (H302). Store at 2-8°C.
Is 2-Benzyloxy-1-methylpyridinium triflate a controlled substance?
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There is no information available to suggest that 2-Benzyloxy-1-methylpyridinium triflate is a controlled substance.
How is 2-Benzyloxy-1-methylpyridinium triflate packed and shipped?
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This chemical is typically supplied in secure packaging suitable for laboratory reagents and is exported globally by Tech Serve Solutions in compliance with international shipping regulations for chemicals.
How can I request a sample or quote for 2-Benzyloxy-1-methylpyridinium triflate?
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To request a sample or a quotation, please visit the Tech Serve Solutions website or contact our sales team directly through the provided contact channels.
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