3,4,5-Trifluoroaniline
3,4,5-Trifluoroaniline (CAS 163733-96-8) is a fluorinated aromatic amine with the molecular formula F 3 C 6 H 2 NH 2 and a molecular weight of 147.10 g/mol. This compound serves as a valuable building block in organic synthesis. Its trifluorinated phenyl ring and reactive amine group make it suitable for incorporation into diverse molecular architectures, particularly in the development of novel materials and biologically active compounds. Supplied by TSS with an assay of 98%, it is ideal for research and development purposes.
- Synonyms
- 163733-96-8F3C6H2NH2

Organic Synthesis Intermediate
3,4,5-Trifluoroaniline is utilised as a key intermediate in the synthesis of complex organic molecules. Its structure allows for various functionalisation reactions, enabling the creation of novel compounds for research.
Pharmaceutical Research
This compound can be employed in the early stages of drug discovery and development. The presence of fluorine atoms can favourably modulate the pharmacokinetic and pharmacodynamic properties of potential drug candidates.
Material Science
As a fluorinated building block, 3,4,5-Trifluoroaniline may be incorporated into polymers or advanced materials. Fluorine substitution often imparts unique properties such as thermal stability and altered electronic characteristics.
| Molecular weight | 147.10 |
|---|---|
| Linear formula | F3C6H2NH2 |
| Assay | 98% |
| Melting point | 61-64 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4,5-Trifluoroaniline used for?
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3,4,5-Trifluoroaniline is primarily used as a building block in organic synthesis, with potential applications in pharmaceutical research and material science due to its fluorinated aromatic structure.
What is the CAS number and chemical formula for 3,4,5-Trifluoroaniline?
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The CAS number is 163733-96-8 and the linear chemical formula is F 3 C 6 H 2 NH 2 .
What grade and purity does Tech Serve Solutions supply for 3,4,5-Trifluoroaniline?
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Tech Serve Solutions supplies 3,4,5-Trifluoroaniline with a minimum assay of 98%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should 3,4,5-Trifluoroaniline be handled safely?
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3,4,5-Trifluoroaniline is classified as a Warning substance (GHS07) with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes.
Is 3,4,5-Trifluoroaniline a controlled substance?
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The provided data does not indicate that 3,4,5-Trifluoroaniline is a controlled substance.
How is 3,4,5-Trifluoroaniline packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, handles the packing and export of chemicals like 3,4,5-Trifluoroaniline in compliance with international shipping regulations.
How can I request a quote or sample for 3,4,5-Trifluoroaniline?
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To request a quote or a sample of 3,4,5-Trifluoroaniline, please contact the Tech Serve Solutions sales team through the designated channels on our website.
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