3-Chlorobenzyl bromide
3-Chlorobenzyl bromide (CAS: 766-80-3) is a halogenated organic compound with the chemical formula ClC6H4CH2Br and a molecular weight of 205.48 g/mol. This aryl compound serves as a valuable building block in chemical synthesis. It is primarily utilised in the creation of various organic molecules, including thioethers and complex heterocyclic compounds, making it a useful reagent in research and development laboratories.
- IUPAC
- α-Bromo-3-chlorotoluene
Synthesis of Benzyl Thioethers
3-Chlorobenzyl bromide is employed as a key reagent in the synthesis of both symmetrical and unsymmetrical benzyl thioethers. Its reactivity facilitates the introduction of the 3-chlorobenzyl moiety into organic structures.
Precursor for Benzimidazole Derivatives
This compound has been documented as a starting material in the preparation of specific benzimidazole derivatives. For instance, it was used in the synthesis of 1-(3-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole dihydrochloride.
Organic Synthesis Building Block
As a halogenated hydrocarbon and an organic building block, 3-Chlorobenzyl bromide is utilized in various organic synthesis pathways. Its structure allows for diverse chemical transformations in the development of novel compounds.
| Molecular weight | 205.48 |
|---|---|
| Linear formula | ClC6H4CH2Br |
| Assay | 97% |
| Boiling point | 109-110 °C/12 mmHg(lit.) |
| Density | 1.565 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.588(lit.) |
| Application | 3-Chlorobenzyl bromide was used in the synthesis of symmetrical and unsymmetrical benzyl thioethers1. It was used as starting reagent during the synthesis of 1-(3-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole dihydrochloride2. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chlorobenzyl bromide primarily used for?
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3-Chlorobenzyl bromide is used as a building block in organic synthesis, notably for the preparation of benzyl thioethers and certain benzimidazole derivatives.
What are the CAS number and chemical formula for 3-Chlorobenzyl bromide?
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The CAS number for 3-Chlorobenzyl bromide is 766-80-3, and its chemical formula is ClC6H4CH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chlorobenzyl bromide with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 3-Chlorobenzyl bromide be handled safely?
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3-Chlorobenzyl bromide is a danger to health, causing severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including face shields, gloves, goggles, and suitable respirator filters, in a well-ventilated area. Immediately consult safety data sheets for detailed handling procedures.
Is 3-Chlorobenzyl bromide available for export?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including 3-Chlorobenzyl bromide.
How can I request a quote or sample for 3-Chlorobenzyl bromide?
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Please contact our sales team directly through the website or by phone to request a quotation or a sample of 3-Chlorobenzyl bromide.
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