Fmoc-Cys(Trt)-OPfp
Nα-Fmoc-S-trityl-L-cysteine pentafluorophenyl ester (CAS: 115520-21-3) is a key protected amino acid derivative crucial for peptide synthesis. With the empirical formula C43H30F5NO4S and a molecular weight of 751.76 g/mol, this compound facilitates controlled peptide chain elongation. Its specific protection strategy makes it valuable in complex biochemical research and the synthesis of peptide-based therapeutics and diagnostics.
- IUPAC
- Nα-Fmoc-S-trityl-L-cysteine pentafluorophenyl ester
Peptide Synthesis
This Fmoc-protected cysteine derivative is extensively used in solid-phase and solution-phase peptide synthesis. The Trityl (Trt) protecting group on the thiol side chain offers stability during coupling steps and is selectively removable under specific conditions, enabling precise peptide construction.
Biochemical Research
It serves as a building block in research focusing on modified peptides, peptidomimetics, and conjugates. Its incorporation allows for the introduction of cysteine residues into peptides for studies involving disulfide bond formation, protein folding, or site-specific modifications.
Chemical Biology
Used in the development of peptides for chemical biology applications, such as bioconjugation or creating probes. The protected thiol functionality allows for later selective reactions after peptide assembly.
| Molecular weight | 751.76 |
|---|---|
| Empirical formula | C43H30F5NO4S |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Fmoc-S-trityl-L-cysteine pentafluorophenyl ester used for?
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Nα-Fmoc-S-trityl-L-cysteine pentafluorophenyl ester is primarily used as a protected amino acid building block in peptide synthesis and chemical biology research.
What is the CAS number and molecular formula?
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The CAS number is 115520-21-3 and the empirical formula is C43H30F5NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥98.0% (HPLC). It is supplied for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.
How should Fmoc-Cys(Trt)-OPfp be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator filter (type N95 or P1). Store refrigerated at 2-8°C.
Is this compound a controlled substance?
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The provided data does not indicate that this compound is a controlled substance.
How can I request a sample or a quote?
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Please contact our customer service team through the website to request a sample or a quotation for Fmoc-Cys(Trt)-OPfp.
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Fmoc-Cys(Trt)-OPfp.
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