Fmoc-Cys(tBu)-OPfp

CAS 109434-23-3C28H24F5NO4SChemical Synthesis

Nα-Fmoc-S-tert-butyl-L-cysteine pentafluorophenyl ester (CAS: 109434-23-3) is a protected amino acid derivative with the molecular formula C28H24F5NO4S and a molecular weight of 565.55 g/mol. This compound serves as a key building block in solid-phase peptide synthesis, facilitating the incorporation of cysteine residues into peptide chains. Its carefully designed protecting groups ensure selective reactions and efficient peptide assembly for research and development purposes.

IUPAC: Nα-Fmoc-S-tert-butyl-L-cysteine pentafluorophenyl ester

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Fmoc-Cys(tBu)-OPfp (C28H24F5NO4S) — chemical structure, CAS 109434-23-3; Chemistry, fine chemical supplied by Tech Serve Solutions

AminesAnalytical StandardsAnalytical/ChromatographyBuilding BlocksC12 to C63C13-C26C20 to C30+C22 to C40+Carbonyl CompoundsChemical Synthesis

01 /Applications

Peptide Synthesis

Utilised as an essential component in solid-phase peptide synthesis (SPPS) to introduce cysteine residues into complex peptide sequences. The Fmoc and tBu protecting groups allow for orthogonal deprotection strategies.

Biochemical Research

Serves as a valuable reagent in biochemical research for the synthesis of modified peptides, peptidomimetics, and peptide-based drug candidates. Enables precise control over peptide structure and function.

Medicinal Chemistry

A crucial intermediate in medicinal chemistry for the development of novel therapeutic agents. Its specific structure aids in the creation of peptides with targeted biological activity.

02 /Properties

Molecular weight	565.55
Empirical formula	C28H24F5NO4S
Assay	≥98.0% (TLC)
Grade	purum
Storage temperature	2-8°C

03 /Safety & handling

Water hazard class (WGK, DE)	3
Safety statements (S)	22-24/25

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

109434-23-3

Beilstein registry

5842866

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Cys(tBu)-OPfp used for?

Fmoc-Cys(tBu)-OPfp is primarily used as a protected amino acid building block in solid-phase peptide synthesis (SPPS) for the incorporation of cysteine residues into peptide chains.

What are the CAS number and formula for Fmoc-Cys(tBu)-OPfp?

The CAS number is 109434-23-3 and the molecular formula is C28H24F5NO4S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Cys(tBu)-OPfp in purum grade with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, or EP grade.

How should Fmoc-Cys(tBu)-OPfp be handled and stored?

Handle with care in a well-ventilated area. Avoid contact with skin and eyes. Store at 2-8°C. Refer to the Safety Data Sheet (SDS) for detailed handling and safety information.

Is this compound a controlled substance?

The provided data does not indicate that Fmoc-Cys(tBu)-OPfp is a controlled substance. Please consult relevant regulations for specific requirements.

How can I request a sample or quote for Fmoc-Cys(tBu)-OPfp?

Please contact our sales team via the website or direct email to request a sample or a quotation for Fmoc-Cys(tBu)-OPfp.

How is Fmoc-Cys(tBu)-OPfp packed, shipped, and exported?

Fmoc-Cys(tBu)-OPfp is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions, adhering to all necessary shipping regulations.