Fmoc-D-Cys(Trt)-OH
Fmoc-D-Cys(Trt)-OH (CAS: 167015-11-4) is a protected amino acid derivative with the molecular formula C37H31NO4S and a molecular weight of 585.71 g/mol. This compound is essential in peptide synthesis, particularly for incorporating D-cysteine residues. The Fmoc group allows for selective deprotection under mild basic conditions, while the Trityl group serves as a robust protecting group for the thiol side chain, safeguarding it during solid-phase peptide synthesis (SPPS).
- IUPAC
- Nα-Fmoc-S-trityl-D-cysteine
Peptide Synthesis
Fmoc-D-Cys(Trt)-OH is a key building block for synthesizing peptides containing D-cysteine. It is widely used in Solid-Phase Peptide Synthesis (SPPS) employing Fmoc chemistry, allowing for the controlled assembly of complex peptide sequences.
Chemical Biology Research
This protected amino acid is valuable in chemical biology for creating modified peptides, peptidomimetics, and probes. Its unique structure enables researchers to study protein-ligand interactions and develop novel biologically active molecules.
Organic Synthesis
Beyond peptides, Fmoc-D-Cys(Trt)-OH serves as a versatile chiral intermediate in complex organic synthesis. Its functional groups can be selectively manipulated for the construction of intricate molecular architectures.
| Molecular weight | 585.71 |
|---|---|
| Empirical formula | C37H31NO4S |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Cys(Trt)-OH used for?
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Fmoc-D-Cys(Trt)-OH is primarily used as a building block in peptide synthesis, particularly for incorporating D-cysteine residues into peptide chains using Fmoc chemistry. It is also utilised in chemical biology and organic synthesis.
What are the CAS number and formula for Fmoc-D-Cys(Trt)-OH?
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The CAS number for Fmoc-D-Cys(Trt)-OH is 167015-11-4, and its molecular formula is C37H31NO4S.
What grade and purity does Tech Serve Solutions supply for Fmoc-D-Cys(Trt)-OH?
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Tech Serve Solutions supplies Fmoc-D-Cys(Trt)-OH with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for Fmoc-D-Cys(Trt)-OH?
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Appropriate personal protective equipment, including eyeshields and gloves, should be worn when handling Fmoc-D-Cys(Trt)-OH. A type N95 (US) or P1 (EN143) respirator filter is recommended. The substance is classified with a WGK of 3 in Germany, indicating a high hazard to water.
How is Fmoc-D-Cys(Trt)-OH stored, packed, and shipped?
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This product requires storage at 2-8°C. Tech Serve Solutions ensures proper packaging and export compliance for global distribution.
How can I request a quote or sample of Fmoc-D-Cys(Trt)-OH?
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To request a quote or sample, please contact our sales team through the website or by phone. We are happy to assist with your research and synthesis needs.
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