Fmoc-D-Asp(OtBu)-OH
Fmoc-D-Asp(OtBu)-OH (CAS: 112883-39-3; C23H25NO6) is a tert-butyl ester derivative of Fmoc-protected D-aspartic acid. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), particularly for incorporating D-aspartic acid residues into peptide chains. Its properties facilitate controlled peptide assembly for research and development in chemical biology and synthesis.
- IUPAC
- Fmoc-D-aspartic acid 4-tert-butyl ester
- Synonyms
- Fmoc-D-aspartic acid 4-tert-butyl ester
Peptide Synthesis
Fmoc-D-Asp(OtBu)-OH is widely employed in solid-phase peptide synthesis (SPPS) for the controlled incorporation of D-aspartic acid. The Fmoc group allows for orthogonal deprotection strategies, while the tert-butyl ester protects the side-chain carboxyl group.
Chemical Biology Research
This derivative is used in the synthesis of peptides and peptidomimetics for studying biological processes. Its incorporation can introduce specific structural or functional modifications to biomolecules.
Drug Discovery and Development
As a key intermediate in peptide synthesis, Fmoc-D-Asp(OtBu)-OH finds application in the development of peptide-based therapeutics and diagnostics. It aids in creating novel peptide sequences with enhanced stability or specific biological activity.
| Molecular weight | 411.45 |
|---|---|
| Empirical formula | C23H25NO6 |
| Assay | 98% |
| Melting point | 146-151 °C |
Hazard statements
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P501Dispose of contents and container per local regulations
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Asp(OtBu)-OH used for?
+
Fmoc-D-Asp(OtBu)-OH is primarily used as a building block in solid-phase peptide synthesis (SPPS) for the incorporation of Fmoc-protected D-aspartic acid residues, contributing to peptide research and chemical synthesis.
What is the CAS number and formula for Fmoc-D-Asp(OtBu)-OH?
+
The CAS number for Fmoc-D-Asp(OtBu)-OH is 112883-39-3, and its empirical formula is C23H25NO6.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Fmoc-D-Asp(OtBu)-OH with an assay of 98%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for Fmoc-D-Asp(OtBu)-OH?
+
Fmoc-D-Asp(OtBu)-OH is classified as Warning with hazard statement H410 (Very toxic to aquatic life with long lasting effects). Handle with appropriate personal protective equipment in a well-ventilated area, and avoid release into the environment. Refer to the Safety Data Sheet (SDS) for comprehensive safety information.
How is Fmoc-D-Asp(OtBu)-OH packed, shipped, and exported?
+
Fmoc-D-Asp(OtBu)-OH is packed and shipped according to international regulations for chemical transport, including UN 3077 classification. Tech Serve Solutions is an experienced global supplier and exporter.
How can I request a sample or quote for Fmoc-D-Asp(OtBu)-OH?
+
To request a sample or obtain a quote for Fmoc-D-Asp(OtBu)-OH, please contact our sales team through the website or by phone, providing your details and the quantity required.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis