Fmoc-D-Bpa-OH
Fmoc-D-Bpa-OH (CAS: 117666-97-4) is an unnatural amino acid derivative with the molecular formula C31H25NO5 and a molecular weight of 491.53 g/mol. This compound is a protected D-phenylalanine derivative featuring a benzophenone moiety. It serves as a valuable building block in peptide synthesis and chemical biology research, enabling the incorporation of photoactivatable or structurally unique residues into peptides.
- IUPAC
- Fmoc-4-benzoyl-D-phenylalanine
Peptide Synthesis
Fmoc-D-Bpa-OH is utilized as a building block in solid-phase peptide synthesis (SPPS) and solution-phase peptide synthesis. Its unnatural structure allows for the introduction of specific functionalities and conformational constraints into peptide chains.
Chemical Biology
The compound finds application in chemical biology for creating modified peptides. The benzophenone group can act as a photoaffinity label, enabling studies of biomolecular interactions and mechanisms.
Drug Discovery
As an unnatural amino acid derivative, Fmoc-D-Bpa-OH can be incorporated into peptide-based drug candidates to enhance stability, receptor binding, or pharmacokinetic properties.
Biochemical Research
Researchers use this compound to explore structure-activity relationships in peptides and to develop novel probes for biological systems.
| Molecular weight | 491.53 |
|---|---|
| Empirical formula | C31H25NO5 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Bpa-OH used for?
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Fmoc-D-Bpa-OH is primarily used as a building block in peptide synthesis and chemical biology research, allowing for the incorporation of unnatural amino acid residues with specific properties into peptides.
What is the CAS number and formula for Fmoc-D-Bpa-OH?
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The CAS number for Fmoc-D-Bpa-OH is 117666-97-4, and its empirical formula is C31H25NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Bpa-OH with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling Fmoc-D-Bpa-OH?
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Handling Fmoc-D-Bpa-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified under WGK 2 in Germany.
How is Fmoc-D-Bpa-OH packed, shipped, and exported?
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Fmoc-D-Bpa-OH is typically packed under refrigeration (2-8°C) and exported following all relevant regulations for chemical substances.
How can I request a sample or quote for Fmoc-D-Bpa-OH?
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To request a sample or a quotation for Fmoc-D-Bpa-OH, please contact our sales team through the website or by phone.
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