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Fmoc-D-Asn(Trt)-OH

CAS 180570-71-2C38H32N2O5Chemical Synthesis

Fmoc-D-Asn(Trt)-OH (CAS: 180570-71-2) is a derivative of the D-enantiomer of asparagine, protected with the Fmoc group and the trityl side-chain protecting group. With a molecular formula of C38H32N2O5, this compound is primarily utilised in solid-phase peptide synthesis (SPPS) and solution-phase peptide chemistry. Its structure facilitates controlled amino acid coupling, making it valuable for constructing complex peptide sequences and peptidomimetics in research and development.

IUPAC
Fmoc-N-trityl-D-asparagine
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Fmoc-D-Asn(Trt)-OH (C38H32N2O5) — chemical structure, CAS 180570-71-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino Acid DerivativesChemical BiologyChemical SynthesisPeptide ChemistryStandard Fmoc-D-Amino Acids
01 /Applications

Solid-Phase Peptide Synthesis (SPPS)

Fmoc-D-Asn(Trt)-OH is widely employed in SPPS to incorporate D-asparagine residues into peptide chains. The Fmoc group allows for base-labile deprotection, while the trityl group protects the asparagine side chain during coupling steps.

Peptide Library Synthesis

This protected amino acid is crucial for generating diverse peptide libraries used in drug discovery and biochemical research. Its specific protection scheme enables regioselective elongation of peptide sequences.

Biochemical Research

Researchers utilise Fmoc-D-Asn(Trt)-OH in studies involving modified peptides, peptidomimetics, and other biologically active molecules where stereochemical integrity and controlled synthesis are paramount.

Chemical Synthesis

It serves as a building block in complex organic synthesis, particularly where a protected D-asparagine moiety is required for constructing larger, specialised molecules.

02 /Properties
Molecular weight596.67
Empirical formulaC38H32N2O5
Assay97%
Storage temperature2-8°C
Melting point211-216 °C
03 /Identifiers & registry
CAS number
180570-71-2
MDL number
MFCD00151919
04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Fmoc-D-Asn(Trt)-OH used for?

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Fmoc-D-Asn(Trt)-OH is used in solid-phase and solution-phase peptide synthesis for incorporating the protected D-asparagine residue into peptide chains, particularly in research and chemical biology applications.

What are the CAS number and formula for Fmoc-D-Asn(Trt)-OH?

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The CAS number is 180570-71-2, and the empirical formula is C38H32N2O5.

What grade and purity does Tech Serve Solutions supply for Fmoc-D-Asn(Trt)-OH?

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Tech Serve Solutions supplies Fmoc-D-Asn(Trt)-OH with an assay of 97%. This product is suitable for research and chemical synthesis purposes and is not supplied as USP, BP, or EP grade.

What are the safety and handling recommendations for Fmoc-D-Asn(Trt)-OH?

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Fmoc-D-Asn(Trt)-OH should be stored at 2-8°C. Please refer to the Safety Data Sheet (SDS) for detailed handling, safety, and disposal information. Always use appropriate personal protective equipment.

How is Fmoc-D-Asn(Trt)-OH packed, shipped, and exported?

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Fmoc-D-Asn(Trt)-OH is carefully packed to ensure stability during transit. Tech Serve Solutions is a global supplier and exporter experienced in handling and shipping fine chemicals worldwide, adhering to all relevant regulations.

How can I request a sample or quote for Fmoc-D-Asn(Trt)-OH?

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To request a sample or a formal quotation, please contact our sales team through the website or by phone. Provide the product name and CAS number for prompt service.

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