Fmoc-D-Ala-OH
Fmoc-D-Ala-OH (CAS 79990-15-1), with the molecular formula C18H17NO4 and a molecular weight of 311.33, is a protected amino acid derivative. It is primarily utilised in solid-phase peptide synthesis (SPPS) and in the construction of peptides containing D-alanine. This compound serves as a crucial building block for researchers and chemists engaged in peptide-based drug discovery, biochemical research, and the synthesis of complex peptides.
- IUPAC
- Fmoc-D-alanine
- Synonyms
- Fmoc-D-alanine
Peptide Synthesis
Fmoc-D-Ala-OH is a key reagent in Fmoc solid-phase peptide synthesis (SPPS). It allows for the controlled incorporation of the non-proteinogenic D-alanine enantiomer into peptide sequences.
Drug Discovery
Used as a building block in the synthesis of peptide-based therapeutics and peptidomimetics. The inclusion of D-amino acids can confer enhanced stability and altered biological activity to peptides.
Biochemical Research
Facilitates the study of peptide structure-activity relationships and the development of novel peptides for research applications in various life science disciplines.
| Molecular weight | 311.33 |
|---|---|
| Empirical formula | C18H17NO4 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]20/D +18.5±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Ala-OH used for?
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Fmoc-D-Ala-OH is primarily used in solid-phase peptide synthesis (SPPS) and for constructing peptides that incorporate D-alanine, a non-natural amino acid, often to enhance stability or modify biological activity in drug discovery and research.
What are the CAS number and formula for Fmoc-D-Ala-OH?
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The CAS number for Fmoc-D-Ala-OH is 79990-15-1, and its empirical formula is C18H17NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Ala-OH with an assay of ≥98.0% determined by HPLC. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for Fmoc-D-Ala-OH?
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When handling Fmoc-D-Ala-OH, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3, indicating a high hazard to water.
How is Fmoc-D-Ala-OH shipped and exported?
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Fmoc-D-Ala-OH requires storage at 2-8°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring appropriate packaging and documentation for international shipments.
How can I request a sample or quote for Fmoc-D-Ala-OH?
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To request a sample or a quotation for Fmoc-D-Ala-OH, please contact our sales team through the website or via the provided contact details.
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