2-Bromophenyl isocyanate
2-Bromophenyl isocyanate (CAS: 1592-00-3, BrC6H4NCO) is a key organic building block and intermediate, with a molecular weight of 198.02 g/mol. This compound is primarily utilised in chemical synthesis, particularly in the creation of complex molecules. Its reactive isocyanate group lends itself to diverse chemical transformations, making it valuable for researchers and manufacturers in the pharmaceutical and fine chemical sectors.
Synthesis of Size-Complementary Rotaxanes
2-Bromophenyl isocyanate has been employed in the synthesis of rotaxanes, specifically a size-complementary [3] rotaxane featuring an alkylene axle. This application highlights its utility in constructing complex supramolecular architectures.
Preparation of Dihydroindole Urea Derivatives
The compound serves as a precursor in the synthesis of dihydroindole urea derivatives. This demonstrates its role in the development of novel heterocyclic compounds with potential pharmacological interest.
Synthesis of Substituted Diphenylureas
2-Bromophenyl isocyanate is utilised in the preparation of 3-carboxamide substituted diphenylurea compounds. This illustrates its application in creating functionalised urea derivatives for various chemical research purposes.
| Molecular weight | 198.02 |
|---|---|
| Linear formula | BrC6H4NCO |
| Assay | 97% |
| Boiling point | 56-58 °C/0.05 mmHg(lit.) |
| Density | 1.607 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5838(lit.) |
| Application | 2-Bromophenyl isocyanate has been used in the synthesis of:• α-cyclodextrin-based size-complementary [3] rotaxane with an alkylene axle1• dihydroindole urea derivatives2• 3-carboxamide substituted diphenylurea3 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 108 °C / 226.4 °F |
| Transport (UN / ADR) | UN 2206 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 22-23-36/37/38-42 |
| Safety statements (S) | 23-26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromophenyl isocyanate used for?
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2-Bromophenyl isocyanate is primarily used as a building block and intermediate in chemical synthesis, particularly for creating complex organic molecules such as rotaxanes, dihydroindole urea derivatives, and substituted diphenylureas.
What are the CAS number and chemical formula for 2-Bromophenyl isocyanate?
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The CAS number for 2-Bromophenyl isocyanate is 1592-00-3, and its chemical formula is BrC6H4NCO.
What grade and purity does Tech Serve Solutions supply for 2-Bromophenyl isocyanate?
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Tech Serve Solutions supplies 2-Bromophenyl isocyanate with an assay of 97%. This product is typically supplied for research and laboratory use. We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards associated with 2-Bromophenyl isocyanate?
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2-Bromophenyl isocyanate is classified as dangerous. It is harmful if swallowed, causes skin irritation, causes serious eye irritation, is toxic if inhaled, and may cause allergy or asthma symptoms or breathing difficulties if inhaled. It may also cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, must be used when handling.
How is 2-Bromophenyl isocyanate packed, shipped, and exported?
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2-Bromophenyl isocyanate is carefully packed according to international shipping regulations for hazardous materials. Tech Serve Solutions, as a global supplier and exporter, ensures compliance with all relevant transport and customs requirements for worldwide distribution.
How can I request a sample or quote for 2-Bromophenyl isocyanate?
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To request a sample or a quote for 2-Bromophenyl isocyanate, please contact our sales department through the website or by phone. Our team will be pleased to assist you with your inquiry.
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