4-(Benzyloxy)benzyl chloride
4-(Benzyloxy)benzyl chloride (CAS: 836-42-0, Formula: C6H5CH2OC6H4CH2Cl) is a chemical compound with a molecular weight of 232.71 g/mol. Supplied by Tech Serve Solutions with a purity of 97%, this compound serves as a valuable building block in organic synthesis. It is particularly noted for its utility in the preparation of 4-aryl-3,4-dihydropyrimidine-5-carboxylates, a class of compounds known for their diverse biological activities.
- IUPAC
- 4-Chloromethyl-α-phenylanisole
- Synonyms
- 4-Chloromethyl-α-phenylanisole
Synthesis of Dihydropyrimidines
4-(Benzyloxy)benzyl chloride is employed as a key intermediate in the synthesis of 4-aryl-3,4-dihydropyrimidine-5-carboxylates (DHPMs). These DHPMs are a significant class of heterocyclic compounds exhibiting a broad range of pharmacological properties.
Organic Building Block
As an organic building block, this compound facilitates the introduction of the 4-(benzyloxy)benzyl moiety into various molecular structures. Its reactive benzyl chloride group allows for facile nucleophilic substitution reactions in complex synthetic pathways.
Chemical Synthesis Intermediate
This reagent is utilised in various chemical synthesis processes where the protected benzyl ether functionality is required. It is suitable for research and development purposes in medicinal chemistry and materials science.
| Molecular weight | 232.71 |
|---|---|
| Linear formula | C6H5CH2OC6H4CH2Cl |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | 4-(benzyloxy)benzyl chloride is used in the preparation of 4-aryl-3,4-dihydropyrimidine-5-carboxylates (DHPMs) which exhibits a wide spectrum of biological effects1. |
| Melting point | 77-79 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Benzyloxy)benzyl chloride used for?
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4-(Benzyloxy)benzyl chloride is primarily used as a building block in organic synthesis, notably in the preparation of 4-aryl-3,4-dihydropyrimidine-5-carboxylates, which possess a wide spectrum of biological effects.
What are the CAS number and chemical formula for 4-(Benzyloxy)benzyl chloride?
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The CAS number for 4-(Benzyloxy)benzyl chloride is 836-42-0, and its chemical formula is C6H5CH2OC6H4CH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Benzyloxy)benzyl chloride with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 4-(Benzyloxy)benzyl chloride be handled safely?
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4-(Benzyloxy)benzyl chloride is a Danger hazard (H314) that causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area and seek immediate medical attention if exposure occurs.
Is 4-(Benzyloxy)benzyl chloride a controlled substance?
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The provided data does not indicate that 4-(Benzyloxy)benzyl chloride is a controlled substance.
How is 4-(Benzyloxy)benzyl chloride shipped and exported?
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4-(Benzyloxy)benzyl chloride is classified under UN 3261, 8 / PGII, indicating it is a hazardous material requiring specialised shipping and handling procedures for export.
How can I request a quote or sample of 4-(Benzyloxy)benzyl chloride?
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To request a quote or sample, please contact our sales department via the website or by phone, providing the product name and CAS number (836-42-0).
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