Fmoc-Cys(StBu)-OH
Fmoc-Cys(StBu)-OH (CAS: 73724-43-3), also known as Nα-Fmoc-S-tert-butylthio-L-cysteine, is a protected amino acid derivative with the molecular formula C22H25NO4S2 and a molecular weight of 431.57 g/mol. This compound is essential in peptide synthesis and chemical biology due to its protected cysteine residue. It is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- Nα-Fmoc-S-tert-butylthio-L-cysteine
- Synonyms
- Nα-Fmoc-S-tert-butylthio-L-cysteine

Peptide Synthesis
Fmoc-Cys(StBu)-OH is a crucial building block in solid-phase and solution-phase peptide synthesis. The Fmoc group facilitates orthogonal protection strategies, while the tert-butylthio group protects the cysteine thiol.
Chemical Biology
This protected amino acid is employed in chemical biology for the synthesis of modified peptides and proteins, enabling studies of protein structure, function, and interactions.
Organic Synthesis
It serves as a versatile intermediate in complex organic synthesis, particularly where a protected cysteine moiety is required for subsequent chemical transformations.
| Molecular weight | 431.57 |
|---|---|
| Empirical formula | C22H25NO4S2 |
| Assay | ≥95.0% (HPLC) |
| Optical activity | [α]20/D −83±2°, c = 1% in ethyl acetate |
| Storage temperature | 2-8°C |
| Melting point | 73-77 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Cys(StBu)-OH used for?
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Fmoc-Cys(StBu)-OH is primarily used in peptide synthesis and chemical biology as a protected cysteine building block.
What is the CAS number and molecular formula for Fmoc-Cys(StBu)-OH?
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The CAS number is 73724-43-3 and the molecular formula is C22H25NO4S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Cys(StBu)-OH with an assay of ≥95.0% (HPLC). This product is intended for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-Cys(StBu)-OH be handled and stored?
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This compound requires careful handling. Recommended personal protective equipment includes eyeshields and gloves. It should be stored at 2-8°C. Refer to the safety data sheet for full handling instructions.
Is Fmoc-Cys(StBu)-OH a controlled substance?
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The provided data does not indicate that Fmoc-Cys(StBu)-OH is a controlled substance.
How is Fmoc-Cys(StBu)-OH packaged and exported?
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Fmoc-Cys(StBu)-OH is carefully packaged to maintain its integrity during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Fmoc-Cys(StBu)-OH?
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Please contact our sales team via the website or direct inquiry to request a sample or a quotation for Fmoc-Cys(StBu)-OH.
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